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    SENP6 SUMO specific peptidase 6 [ Canis lupus familiaris (dog) ]

    Gene ID: 481883, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SENP6provided by VGNC
    Official Full Name
    SUMO specific peptidase 6provided by VGNC
    Primary source
    VGNC:VGNC:54992
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SENP6 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (37922270..38039671)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (37097888..37215412)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (37445314..37563688)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (37325685..37443251)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (37316954..37432424)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene high mobility group protein B1-like Neighboring gene beta-secretase 2-like Neighboring gene U6 spliceosomal RNA Neighboring gene double homeobox protein A-like Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SUMO-specific endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein desumoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of kinetochore assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of spindle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sentrin-specific protease 6; LOW QUALITY PROTEIN: sentrin-specific protease 6
    Names
    SUMO1/sentrin specific peptidase 6
    XP_005627596.1
    XP_005627598.1
    XP_005627600.1
    XP_013973587.1
    XP_013973588.1
    XP_013973589.1
    XP_022281968.1
    XP_038348189.1
    XP_038348190.1
    XP_038348191.1
    XP_038348192.1
    XP_038348193.1
    XP_038348194.1
    XP_038348195.1
    XP_038348196.1
    XP_038348197.1
    XP_038348198.1
    XP_038348199.1
    XP_038410476.1
    XP_038410477.1
    XP_038410478.1
    XP_038410479.1
    XP_038410480.1
    XP_038410482.1
    XP_038410483.1
    XP_038410484.1
    XP_038410485.1
    XP_038410486.1
    XP_038410487.1
    XP_038474337.1
    XP_038474338.1
    XP_038474339.1
    XP_038474340.1
    XP_038474341.1
    XP_038474342.1
    XP_038474343.1
    XP_038474344.1
    XP_038474345.1
    XP_038474346.1
    XP_038474347.1
    XP_038526669.1
    XP_038526678.1
    XP_038526685.1
    XP_038526699.1
    XP_038539915.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      37922270..38039671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038683987.1 → XP_038539915.1  LOW QUALITY PROTEIN: sentrin-specific protease 6 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KCM8, A0A8C0TFJ1
      Conserved Domains (2) summary
      COG5160
      Location:664 → 776
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:976 → 1070
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      37325685..37443251
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038492271.1 → XP_038348199.1  sentrin-specific protease 6 isoform X11

      Conserved Domains (1) summary
      COG5160
      Location:657 → 686
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]

    2. XM_038492261.1 → XP_038348189.1  sentrin-specific protease 6 isoform X2

    3. XM_038492265.1 → XP_038348193.1  sentrin-specific protease 6 isoform X1

      Conserved Domains (2) summary
      COG5160
      Location:664 → 776
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:976 → 1070
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    4. XM_038492262.1 → XP_038348190.1  sentrin-specific protease 6 isoform X3

    5. XM_038492263.1 → XP_038348191.1  sentrin-specific protease 6 isoform X4

    6. XM_038492266.1 → XP_038348194.1  sentrin-specific protease 6 isoform X6

    7. XM_038492270.1 → XP_038348198.1  sentrin-specific protease 6 isoform X10

    8. XM_038492264.1 → XP_038348192.1  sentrin-specific protease 6 isoform X5

    9. XM_038492267.1 → XP_038348195.1  sentrin-specific protease 6 isoform X7

      Conserved Domains (2) summary
      COG5160
      Location:590 → 702
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:902 → 996
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    10. XM_038492268.1 → XP_038348196.1  sentrin-specific protease 6 isoform X8

      Conserved Domains (2) summary
      COG5160
      Location:589 → 701
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:901 → 995
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    11. XM_038492269.1 → XP_038348197.1  sentrin-specific protease 6 isoform X9

      Conserved Domains (2) summary
      COG5160
      Location:583 → 695
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:895 → 989
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      37316954..37432424
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038618419.1 → XP_038474347.1  sentrin-specific protease 6 isoform X21

      Conserved Domains (1) summary
      COG5160
      Location:657 → 686
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]

    2. XM_038618409.1 → XP_038474337.1  sentrin-specific protease 6 isoform X12

    3. XM_038618413.1 → XP_038474341.1  sentrin-specific protease 6 isoform X1

      Conserved Domains (2) summary
      COG5160
      Location:664 → 776
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:976 → 1070
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    4. XM_038618410.1 → XP_038474338.1  sentrin-specific protease 6 isoform X13

    5. XM_038618411.1 → XP_038474339.1  sentrin-specific protease 6 isoform X14

    6. XM_038618414.1 → XP_038474342.1  sentrin-specific protease 6 isoform X16

    7. XM_038618418.1 → XP_038474346.1  sentrin-specific protease 6 isoform X20

    8. XM_038618412.1 → XP_038474340.1  sentrin-specific protease 6 isoform X15

    9. XM_038618415.1 → XP_038474343.1  sentrin-specific protease 6 isoform X17

    10. XM_038618416.1 → XP_038474344.1  sentrin-specific protease 6 isoform X18

    11. XM_038618417.1 → XP_038474345.1  sentrin-specific protease 6 isoform X19

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      37445314..37563688
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038554559.1 → XP_038410487.1  sentrin-specific protease 6 isoform X31

      UniProtKB/TrEMBL
      A0A8I3N3Y7
      Conserved Domains (1) summary
      COG5160
      Location:657 → 686
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]

    2. XM_038554548.1 → XP_038410476.1  sentrin-specific protease 6 isoform X22

      UniProtKB/TrEMBL
      A0A8C0KCM8, A0A8C0TEP7, A0A8P0N5Q8

    3. XM_038554552.1 → XP_038410480.1  sentrin-specific protease 6 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KCM8, A0A8C0TFJ1
      Conserved Domains (2) summary
      COG5160
      Location:664 → 776
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:976 → 1070
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    4. XM_038554549.1 → XP_038410477.1  sentrin-specific protease 6 isoform X23

      UniProtKB/TrEMBL
      A0A8C0KCM8

    5. XM_038554550.1 → XP_038410478.1  sentrin-specific protease 6 isoform X24

      UniProtKB/TrEMBL
      A0A8C0KCM8, A0A8C0TBK0, A0A8P0PBU7

    6. XM_038554554.1 → XP_038410482.1  sentrin-specific protease 6 isoform X26

      UniProtKB/TrEMBL
      A0A8C0KCD8, A0A8C0KCM8, A0A8C0MMG0

    7. XM_038554558.1 → XP_038410486.1  sentrin-specific protease 6 isoform X30

      UniProtKB/TrEMBL
      A0A8C0KCM8

    8. XM_038554551.1 → XP_038410479.1  sentrin-specific protease 6 isoform X25

      UniProtKB/TrEMBL
      A0A8C0KCM8

    9. XM_038554555.1 → XP_038410483.1  sentrin-specific protease 6 isoform X27

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:590 → 702
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:902 → 996
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    10. XM_038554556.1 → XP_038410484.1  sentrin-specific protease 6 isoform X28

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:589 → 701
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:901 → 995
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    11. XM_038554557.1 → XP_038410485.1  sentrin-specific protease 6 isoform X29

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:583 → 695
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:895 → 989
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      37097888..37215412
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038670771.1 → XP_038526699.1  sentrin-specific protease 6 isoform X41

      UniProtKB/TrEMBL
      A0A8I3N3Y7
      Conserved Domains (1) summary
      COG5160
      Location:657 → 686
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]

    2. XM_014118112.3 → XP_013973587.1  sentrin-specific protease 6 isoform X32

      UniProtKB/TrEMBL
      A0A8C0KCM8, A0A8C0TEP7, A0A8P0N5Q8
      Conserved Domains (2) summary
      COG5160
      Location:694 → 806
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:1006 → 1082
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    3. XM_005627539.4 → XP_005627596.1  sentrin-specific protease 6 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KCM8, A0A8C0TFJ1
      Conserved Domains (2) summary
      COG5160
      Location:664 → 776
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:976 → 1070
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    4. XM_022426260.2 → XP_022281968.1  sentrin-specific protease 6 isoform X33

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:693 → 805
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:1005 → 1081
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    5. XM_014118113.3 → XP_013973588.1  sentrin-specific protease 6 isoform X34

      UniProtKB/TrEMBL
      A0A8C0KCM8, A0A8C0TBK0, A0A8P0PBU7
      Conserved Domains (2) summary
      COG5160
      Location:687 → 799
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:999 → 1075
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    6. XM_005627541.4 → XP_005627598.1  sentrin-specific protease 6 isoform X36

      UniProtKB/TrEMBL
      A0A8C0KCD8, A0A8C0KCM8, A0A8C0MMG0
      Conserved Domains (2) summary
      COG5160
      Location:657 → 769
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:969 → 1045
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    7. XM_005627543.4 → XP_005627600.1  sentrin-specific protease 6 isoform X40

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:487 → 599
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:799 → 875
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    8. XM_014118114.3 → XP_013973589.1  sentrin-specific protease 6 isoform X35

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:685 → 797
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:997 → 1073
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    9. XM_038670741.1 → XP_038526669.1  sentrin-specific protease 6 isoform X37

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:590 → 702
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:902 → 996
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    10. XM_038670750.1 → XP_038526678.1  sentrin-specific protease 6 isoform X38

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:589 → 701
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:901 → 995
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

    11. XM_038670757.1 → XP_038526685.1  sentrin-specific protease 6 isoform X39

      UniProtKB/TrEMBL
      A0A8C0KCM8
      Conserved Domains (2) summary
      COG5160
      Location:583 → 695
      ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
      cl23802
      Location:895 → 989
      Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
    Nucleotide Protein
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