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    LOC6037551 acetylcholinesterase [ Culex quinquefasciatus (southern house mosquito) ]

    Gene ID: 6037551, updated on 26-Mar-2024

    Summary

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    Gene symbol
    LOC6037551
    Gene description
    acetylcholinesterase
    See related
    VectorBase:CQUJHB013404; EnsemblRapid:LOC6037551
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Culex quinquefasciatus
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Culicini; Culex; Culex
    Also known as
    AChE; ace1; AChE1; ace-1
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    Genomic context

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    See LOC6037551 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    100 current VPISU_Cqui_1.0_pri_paternal (GCF_015732765.1) 3 NC_051863.1 (71649064..71897754, complement)

    Chromosome 3 - NC_051863.1Genomic Context describing neighboring genes Neighboring gene RING finger protein 44 Neighboring gene beta-catenin-like protein 1 Neighboring gene uncharacterized LOC6044862 Neighboring gene uncharacterized LOC6044863 Neighboring gene fibroblast growth factor receptor 3 Neighboring gene uncharacterized LOC119769399 Neighboring gene heparan sulfate 6-O-sulfotransferase Neighboring gene uncharacterized LOC119770226

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_051863.1 Chromosome 3 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Point mutations associated with organophosphate and carbamate resistance in Chinese strains of Culex pipiens quinquefasciatus (Diptera: Culicidae). Zhao M, et al. PLoS One, 2014. PMID 24788312, Free PMC Article
    2. First molecular genotyping of insensitive acetylcholinesterase associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia. Low VL, et al. Pest Manag Sci, 2013 Dec. PMID 23404830
    3. High incidence of ace-1 duplicated haplotypes in resistant Culex pipiens mosquitoes from Algeria. Alout H, et al. Insect Biochem Mol Biol, 2011 Jan. PMID 20887788
    4. Comparison of Anopheles gambiae and Culex pipiens acetycholinesterase 1 biochemical properties. Alout H, et al. Comp Biochem Physiol B Biochem Mol Biol, 2008 Jul. PMID 18455457
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Missense mutation in acetylcholinesterase are associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia.
      Title: First molecular genotyping of insensitive acetylcholinesterase associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia.
    2. There is high incidence of ace-1 duplicated haplotypes in resistant Culex pipiens mosquitoes from Algeria.
      Title: High incidence of ace-1 duplicated haplotypes in resistant Culex pipiens mosquitoes from Algeria.
    3. acetycholinesterase 1 (AChE1) belonging to both Anopheles gambiae and Culex pipiens seem to share identical properties.
      Title: Comparison of Anopheles gambiae and Culex pipiens acetycholinesterase 1 biochemical properties.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetylcholinesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acetylcholine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in choline metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acetylcholinesterase
    Names
    acetylcholinesterase-1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Culex quinquefasciatus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

    Genomic

    1. NC_051863.1 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

      Range
      71649064..71897754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038261577.1 → XP_038117505.1  acetylcholinesterase isoform X2

      UniProtKB/TrEMBL
      V5W7Z2
      Related
      XP_038117505.1, XM_038261577.1
      Conserved Domains (1) summary
      pfam00135
      Location:137 → 659
      COesterase; Carboxylesterase family

    2. XM_038261578.1 → XP_038117506.1  acetylcholinesterase isoform X3

      UniProtKB/TrEMBL
      V5W7Z2
      Related
      XP_038117506.1, XM_038261578.1
      Conserved Domains (1) summary
      pfam00135
      Location:132 → 654
      COesterase; Carboxylesterase family

    3. XM_038261576.1 → XP_038117504.1  acetylcholinesterase isoform X1

      UniProtKB/TrEMBL
      V5W7Z2
      Related
      XP_038117504.1, XM_038261576.1
      Conserved Domains (1) summary
      pfam00135
      Location:140 → 662
      COesterase; Carboxylesterase family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q867X2.1 GenPept UniProtKB/Swiss-Prot:Q867X2

    Gene LinkOut

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