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    Slc6a4 solute carrier family 6 member 4 [ Peromyscus leucopus (white-footed mouse) ]

    Gene ID: 114691461, updated on 15-Mar-2024

    Summary

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    Gene symbol
    Slc6a4
    Gene description
    solute carrier family 6 member 4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Peromyscus leucopus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Neotominae; Peromyscus
    Orthologs
    human mouse all
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    Genomic context

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    See Slc6a4 in Genome Data Viewer
    Location:
    chromosome: 8b
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    101 current UCI_PerLeu_2.1 (GCF_004664715.2) 8b NC_051086.1 (60273602..60308627)
    100 previous assembly Pero_0.1 (GCF_004664715.1) Unplaced Scaffold NW_021630165.1 (3025464..3060471)

    Chromosome 8b - NC_051086.1Genomic Context describing neighboring genes Neighboring gene transmembrane and immunoglobulin domain containing 1 Neighboring gene U1 spliceosomal RNA Neighboring gene bleomycin hydrolase Neighboring gene small nucleolar RNA SNORA33 Neighboring gene nuclear speckle splicing regulatory protein 1 Neighboring gene EF-hand calcium binding domain 5 Neighboring gene slingshot protein phosphatase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serotonin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serotonin:sodium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in serotonin uptake IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium-dependent serotonin transporter

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Peromyscus leucopus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCI_PerLeu_2.1 Primary Assembly

    Genomic

    1. NC_051086.1 Reference UCI_PerLeu_2.1 Primary Assembly

      Range
      60273602..60308627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028866798.2 → XP_028722631.1  sodium-dependent serotonin transporter

      Conserved Domains (2) summary
      cd11513
      Location:80 → 616
      SLC6sbd_SERT; Na(+)- and Cl(-)-dependent serotonin transporter SERT; solute-binding domain
      pfam03491
      Location:24 → 64
      5HT_transport_N; Serotonin (5-HT) neurotransmitter transporter, N-terminus
    Nucleotide Protein
    Heading Accession and Version

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