Hdac1-ps histone deacetylase 1, pseudogene [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Hdac1-psprovided by MGI
Official Full Name: histone deacetylase 1, pseudogeneprovided by MGI
Primary source: MGI:MGI:3704479
See related: AllianceGenome:MGI:3704479
Gene type: pseudo
RefSeq status: INFERRED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: HD1; RPD3; Hdac1; Gm1824; EG15181; Gm10093
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 17 E3; 17 49.28 cM

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (78798994..78800970)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (78491565..78493541)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Hdac1 is autoregulated.
Title: Autoregulation of mouse histone deacetylase 1 expression.
HDAC1 is a substrate for SUMO-1 (small ubiquitin-related modifier) modification in vitro and in vivo
Title: SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities.
Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells
Title: Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells.
Results present evidence for a precise regulatory mechanism which allows induction of the HDAC1 gene in response to proliferation signals and modulation of HDAC1 expression dependent on intracellular deacetylase levels.
Title: Activation of the mouse histone deacetylase 1 gene by cooperative histone phosphorylation and acetylation.
HDAC1 interacts with p300 C/H3 domain. Its overexpression interferes with either activation or Gal14p300 fusion protein or p53. E1A competes with HDAC1 for C/H3 binding.
Title: Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300.
The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I mediated transcription.
Title: The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.
data indicate that insulin gene expression is decreased on low levels of glucose by recruitment of histone deacetylases Hdac-1 and Hdac-2 to the insulin promoter by pancreatic duodenal homeobox-1 transcription factor Pdx-1
Title: The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose.
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
Title: Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.