Krt33a keratin 33A [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Krt33aprovided by MGI
Official Full Name: keratin 33Aprovided by MGI
Primary source: MGI:MGI:1919138
See related: Ensembl:ENSMUSG00000035592 AllianceGenome:MGI:1919138
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2310015J09Rik
Summary: Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Orthologous to human KRT31 (keratin 31); KRT33A (keratin 33A); and KRT34 (keratin 34). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 11 D; 11 63.35 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (99902025..99907038, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (100011199..100016212, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Chemically induced (ENU) (3)
Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in epithelial cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in intermediate filament organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in intermediate filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin, type I cuticular Ha3-I

Names: K33A; hair keratin, type I Ha3-I; ortholog of keratin, hair, acidic, 3A KRTHA3A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_027983.3 → NP_082259.2 keratin, type I cuticular Ha3-I

See identical proteins and their annotated locations for NP_082259.2

Status: VALIDATED

Source sequence(s)

AK037251

Consensus CDS

CCDS25403.1

UniProtKB/Swiss-Prot

Q8K0Y2, Q9D7C4

Related

ENSMUSP00000018399.3, ENSMUST00000018399.3

Conserved Domains (2) summary

COG3352
Location:252 → 363

FlaC; Archaellum component FlaC [Cell motility]

pfam00038
Location:55 → 366

Filament; Intermediate filament protein