IFNAA interferon alpha-A [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: IFNAA
Gene description: interferon alpha-A
See related: BGD:BT13478
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: IFN-a
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Genomic context

Location:: chromosome: 8

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	8	NC_037335.1 (22998897..22999558)

Chromosome 8 - NC_037335.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2.
Title: Interferon-alpha signalling in bovine adrenal chromaffin cells: involvement of signal-transducer and activator of transcription 1 and 2, extracellular signal-regulated protein kinases 1/2 and serine 31 phosphorylation of tyrosine hydroxylase.
produced in vitro and in vivo in response to noncytopathic bovine viral diarrhea virus in lymph nodes cells expressing the myeloid markers CD14, CD11b, and CD172a
Title: Identification of a cell population that produces alpha/beta interferon in vitro and in vivo in response to noncytopathic bovine viral diarrhea virus.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info	PubMed
enables type I interferon receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in B cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in B cell proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in T cell activation involved in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in humoral immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in natural killer cell activation involved in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of peptidyl-serine phosphorylation of STAT protein	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to exogenous dsRNA	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: interferon alpha-A

Names: interferon-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.