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    Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287644, updated on 28-Oct-2024

    Summary

    Official Symbol
    Phospho1provided by RGD
    Official Full Name
    phosphoethanolamine/phosphocholine phosphatase 1provided by RGD
    Primary source
    RGD:1306182
    See related
    EnsemblRapid:ENSRNOG00000005569 AllianceGenome:RGD:1306182
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable phosphocholine phosphatase activity; phosphoethanolamine phosphatase activity; and pyrophosphatase activity. Predicted to be involved in bone mineralization involved in bone maturation. Predicted to act upstream of or within endochondral ossification. Predicted to be located in extracellular matrix. Predicted to be active in extracellular membrane-bounded organelle. Orthologous to human PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in Muscle (RPKM 221.7), Heart (RPKM 105.3) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Phospho1 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (81258810..81266345)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (80762062..80769596)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (83635557..83643862)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095179 Neighboring gene zinc finger protein 652 Neighboring gene uncharacterized LOC102547047 Neighboring gene ABI family, member 3 Neighboring gene G protein subunit gamma transducin 2 Neighboring gene uncharacterized LOC134480858 Neighboring gene transfer RNA glutamine (anticodon UUG) 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphocholine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphoethanolamine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables pyrophosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in bone mineralization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bone mineralization involved in bone maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within bone mineralization involved in bone maturation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within endochondral ossification ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    phosphoethanolamine/phosphocholine phosphatase
    Names
    phosphatase, orphan 1
    NP_001099303.1
    XP_006247246.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105833.1NP_001099303.1  phosphoethanolamine/phosphocholine phosphatase

      See identical proteins and their annotated locations for NP_001099303.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A0A8I6A6B0, A6HIB0, B5DFB9
      Related
      ENSRNOP00000111048.1, ENSRNOT00000174067.1
      Conserved Domains (1) summary
      pfam06888
      Location:49286
      Put_Phosphatase; Putative Phosphatase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      81258810..81266345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006247184.5XP_006247246.1  phosphoethanolamine/phosphocholine phosphatase isoform X1

      See identical proteins and their annotated locations for XP_006247246.1

      UniProtKB/TrEMBL
      B5DFB9
      Conserved Domains (1) summary
      pfam06888
      Location:27264
      Put_Phosphatase; Putative Phosphatase