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    PF3D7_1116200.1 pyridoxine biosynthesis protein PDX2 [ Plasmodium falciparum 3D7 ]

    Gene ID: 810716, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1116200.1
    Gene description
    pyridoxine biosynthesis protein PDX2
    Locus tag
    PF3D7_1116200.1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Old locus tag
    PF3D7_1116200.2
    Orthologs
    all
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    Genomic context

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    See PF3D7_1116200.1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Sequence:
    Chromosome: 11; NC_037282.1 (615744..617186, complement)

    Chromosome 11 - NC_037282.1Genomic Context describing neighboring genes Neighboring gene rhoptry neck protein 4 Neighboring gene serine esterase, putative Neighboring gene peptidyl-prolyl cis-trans isomerase Neighboring gene guanine nucleotide-exchange factor SEC12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037282.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the vitamin B6 biosynthesis pathway in the human malaria parasite Plasmodium falciparum. Wrenger C, et al. J Biol Chem, 2005 Feb 18. PMID 15590634
    2. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables glutaminase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to singlet oxygen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within vitamin B6 biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyridoxine biosynthesis protein PDX2
    XP_001347840.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037282.1 Reference assembly

      Range
      615744..617186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024473313.1 → XP_024329120.1  pyridoxine biosynthesis protein PDX2 [Plasmodium falciparum 3D7]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2I0C0L8
      Conserved Domains (1) summary
      cl00020
      Location:6 → 172
      GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

    2. XM_001347804.2 → XP_001347840.2  pyridoxine biosynthesis protein PDX2 [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347840.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      A0A143ZYM6, A0A144A0A4, Q5ND68, Q8IIK4
      UniProtKB/TrEMBL
      A0A024W5Z7, A0A024WNX8, A0A2I0C0L6, W4IER9, W7FJS4
      Conserved Domains (1) summary
      cd01749
      Location:6 → 210
      GATase1_PB; Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IIK4.2

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