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    Fam78b family with sequence similarity 78, member B [ Mus musculus (house mouse) ]

    Gene ID: 226610, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Fam78bprovided by MGI
    Official Full Name
    family with sequence similarity 78, member Bprovided by MGI
    Primary source
    MGI:MGI:2443050
    See related
    Ensembl:ENSMUSG00000060568 AllianceGenome:MGI:2443050
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C030014K22Rik; C030020L09Rik
    Summary
    Orthologous to human FAM78B (family with sequence similarity 78 member B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in whole brain E14.5 (RPKM 6.8), CNS E18 (RPKM 6.1) and 17 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam78b in Genome Data Viewer
    Location:
    1 H2.3; 1 74.38 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (166827456..166918871)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (166999851..167091302)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L7A pseudogene Neighboring gene STARR-seq mESC enhancer starr_02937 Neighboring gene predicted gene, 16701 Neighboring gene predicted gene, 33610 Neighboring gene STARR-seq mESC enhancer starr_02940 Neighboring gene predicted gene, 33668 Neighboring gene STARR-seq mESC enhancer starr_02941 Neighboring gene TSPY-like 3 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM78B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001160261.1 → NP_001153733.1  protein FAM78B

      See identical proteins and their annotated locations for NP_001153733.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AC158767, BC132525, CB575012
      Consensus CDS
      CCDS35764.1
      UniProtKB/Swiss-Prot
      A2RSM0, Q8BQN5, Q8CC61
      UniProtKB/TrEMBL
      F6SII3
      Related
      ENSMUSP00000139628.2, ENSMUST00000190081.7

    2. NM_001160262.1 → NP_001153734.1  protein FAM78B

      See identical proteins and their annotated locations for NP_001153734.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
      Source sequence(s)
      AC158767, AK047703, CB575012
      Consensus CDS
      CCDS35764.1
      UniProtKB/Swiss-Prot
      A2RSM0, Q8BQN5, Q8CC61
      UniProtKB/TrEMBL
      F6SII3
      Related
      ENSMUSP00000131620.2, ENSMUST00000165874.8

    3. NM_175461.4 → NP_780670.2  protein FAM78B

      See identical proteins and their annotated locations for NP_780670.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AC158767, BC066094, CB575012
      Consensus CDS
      CCDS35764.1
      UniProtKB/Swiss-Prot
      A2RSM0, Q8BQN5, Q8CC61
      UniProtKB/TrEMBL
      F6SII3
      Related
      ENSMUSP00000117516.2, ENSMUST00000128373.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      166827456..166918871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496789.3 → XP_006496852.1  protein FAM78B isoform X1

      See identical proteins and their annotated locations for XP_006496852.1

      UniProtKB/Swiss-Prot
      A2RSM0, Q8BQN5, Q8CC61
      UniProtKB/TrEMBL
      F6SII3
      Related
      ENSMUSP00000122636.2, ENSMUST00000126198.3
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BQN5.2 GenPept UniProtKB/Swiss-Prot:Q8BQN5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools