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    siva1.L SIVA1, apoptosis-inducing factor L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100037065, updated on 4-Nov-2024

    Summary

    Official Symbol
    siva1.L
    Official Full Name
    SIVA1, apoptosis-inducing factor L homeolog
    Primary source
    Xenbase:XB-GENE-5854269
    Locus tag
    XELAEV_18039747mg
    See related
    EnsemblRapid:ENSXLAG00005019622 AllianceGenome:Xenbase:XB-GENE-5854269
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    siva; siva1; siva2; cd27bp; siva-1; siva-2
    Summary
    Predicted to enable CD27 receptor binding activity and metal ion binding activity. Predicted to act upstream of or within extrinsic apoptotic signaling pathway. Predicted to be located in cytoplasm and nucleus. Orthologous to human SIVA1 (SIVA1 apoptosis inducing factor). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See siva1.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (90946731..90951774)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (76217054..76222157)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene inverted formin, FH2 and WH2 domain containing L homeolog Neighboring gene adenylosuccinate synthase 1 L homeolog Neighboring gene AKT serine/threonine kinase 1 L homeolog Neighboring gene uncharacterized LOC108698804 Neighboring gene zinc finger protein 238, gene 2 L homeolog

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables CD27 receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within extrinsic apoptotic signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    SIVA1, apoptosis-inducing factor L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001097791.1NP_001091260.1  SIVA1, apoptosis-inducing factor L homeolog

      See identical proteins and their annotated locations for NP_001091260.1

      Status: PROVISIONAL

      Source sequence(s)
      BC128981
      UniProtKB/TrEMBL
      A0A974C9D5, A0A974H8M9, A1L1C4
      Related
      ENSXLAP00005057632.1, ENSXLAT00005058984.1
      Conserved Domains (1) summary
      pfam05458
      Location:1163
      Siva; Cd27 binding protein (Siva)

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      90946731..90951774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)