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    tnf-alpha-1 tumor necrosis factor alpha-1 precursor [ Salmo salar (Atlantic salmon) ]

    Gene ID: 100136457, updated on 30-Nov-2023

    Summary

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    Gene symbol
    tnf-alpha-1
    Gene description
    tumor necrosis factor alpha-1 precursor
    See related
    Ensembl:ENSSSAG00000065312
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Salmo salar
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo
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    Genomic context

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    See tnf-alpha-1 in Genome Data Viewer
    Location:
    chromosome: ssa05
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    102 current Ssal_v3.1 (GCF_905237065.1) ssa05 NC_059446.1 (56891823..56893834, complement)
    100 previous assembly ICSASG_v2 (GCF_000233375.1) ssa05 NC_027304.1 (54270847..54272858, complement)

    Chromosome ssa05 - NC_059446.1Genomic Context describing neighboring genes Neighboring gene gamma-aminobutyric acid type B receptor subunit 1 Neighboring gene uncharacterized LOC106605217 Neighboring gene uncharacterized LOC123723743 Neighboring gene uncharacterized LOC106605216

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and expression analysis of tumour necrosis factor-alpha in amoebic gill disease (AGD)-affected Atlantic salmon (Salmo salar L.). Morrison RN, et al. Fish Shellfish Immunol, 2007 Nov. PMID 17566761
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tumor necrosis factor alpha-1 precursor
    Names
    TNF-alpha 1
    tumor necrosis factor alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001123589.1 → NP_001117061.1  tumor necrosis factor alpha-1 precursor

      See identical proteins and their annotated locations for NP_001117061.1

      Status: PROVISIONAL

      Source sequence(s)
      AY929385
      UniProtKB/TrEMBL
      Q0PNB7, Q5BMN3
      Related
      ENSSSAP00000075795.1, ENSSSAT00000109219.2
      Conserved Domains (1) summary
      cd00184
      Location:95 → 244
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    RefSeqs of Annotated Genomes: Salmo salar Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Ssal_v3.1

    Genomic

    1. NC_059446.1 Reference Ssal_v3.1

      Range
      56891823..56893834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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