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    ECU08_0860 Ubiquitin-conjugating enzyme E2 [ Encephalitozoon cuniculi GB-M1 ]

    Gene ID: 859638, updated on 17-May-2024

    Summary

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    Gene symbol
    ECU08_0860
    Gene description
    Ubiquitin-conjugating enzyme E2
    Locus tag
    ECU08_0860
    See related
    MicrosporidiaDB:ECU08_0860; VEuPathDB:ECU08_0860
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Encephalitozoon cuniculi GB-M1 (isolate: GB-M1)
    Lineage
    Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae; Encephalitozoon
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    Genomic context

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    See ECU08_0860 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_003235.1 (100439..100954, complement)

    Chromosome VIII - NC_003235.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene CCR4-NOT core DEDD family RNase subunit POP2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003235.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of transcriptional signals in Encephalitozoon cuniculi widespread among Microsporidia phylum: support for accurate structural genome annotation. Peyretaillade E, et al. BMC Genomics, 2009 Dec 15. PMID 20003517, Free PMC Article
    2. Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi. Katinka MD, et al. Nature, 2001 Nov 22. PMID 11719806
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ubiquitin-conjugating enzyme E2
    NP_597216.1
    • 08_0860, UBIQUITIN-CONJUGATING ENZYME E2-24KD (UBIQUITIN-PROTEIN LIGASE), UBC8_YEAST, gene found by Glimmer

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003235.1 Reference assembly

      Range
      100439..100954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001041825.1 → NP_597216.1  Ubiquitin-conjugating enzyme E2 [Encephalitozoon cuniculi GB-M1]

      See identical proteins and their annotated locations for NP_597216.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      M1K7Z6, Q8SRC0
      Conserved Domains (2) summary
      COG5078
      Location:7 → 148
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cd00195
      Location:7 → 143
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    Nucleotide Protein
    Heading Accession and Version

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