Eid2b EP300 interacting inhibitor of differentiation 2B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Eid2bprovided by MGI
Official Full Name: EP300 interacting inhibitor of differentiation 2Bprovided by MGI
Primary source: MGI:MGI:1924095
See related: Ensembl:ENSMUSG00000070705 AllianceGenome:MGI:1924095
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 3010005C08Rik
Summary: Predicted to enable identical protein binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of myoblast differentiation. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Orthologous to human EID2B (EP300 interacting inhibitor of differentiation 2B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human all
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Genomic context

Location:: 7 A3; 7 16.67 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (27977152..27978916)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (28277706..28280129)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of myoblast differentiation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: EP300-interacting inhibitor of differentiation 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177427.2 → NP_001170898.1 EP300-interacting inhibitor of differentiation 2B

Status: VALIDATED

Source sequence(s)

AC148986

Consensus CDS

CCDS52161.1

UniProtKB/TrEMBL

E9Q2Y0

Related

ENSMUSP00000092235.3, ENSMUST00000094651.4