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    Or5ae1 olfactory receptor family 5 subfamily AE member 1 [ Mus musculus (house mouse) ]

    Gene ID: 258411, updated on 2-Nov-2024

    Summary

    Official Symbol
    Or5ae1provided by MGI
    Official Full Name
    olfactory receptor family 5 subfamily AE member 1provided by MGI
    Primary source
    MGI:MGI:3030124
    See related
    Ensembl:ENSMUSG00000116179 AllianceGenome:MGI:3030124
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr290; MOR254-1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

    See Or5ae1 in Genome Data Viewer
    Location:
    7 D3; 7 48.38 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (84564989..84565936)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (84915781..84916728)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene transformation related protein 63 regulated like, pseudogene 2 Neighboring gene STARR-seq mESC enhancer starr_19443 Neighboring gene predicted gene, 53363 Neighboring gene ubiquitin specific peptidase 46 pseudogene Neighboring gene vomeronasal 2, receptor 65 Neighboring gene predicted gene, 17985

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • MGC157560

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 

    General protein information

    Preferred Names
    olfactory receptor 290
    Names
    GA_x6K02T2NHDJ-11170115-11169168
    olfactory receptor MOR254-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146416.2NP_666528.2  olfactory receptor 290

      See identical proteins and their annotated locations for NP_666528.2

      Status: VALIDATED

      Source sequence(s)
      AC163494
      Consensus CDS
      CCDS21421.1
      UniProtKB/TrEMBL
      Q7TS13, Q8VF61
      Related
      ENSMUSP00000073172.3, ENSMUST00000073468.5
      Conserved Domains (2) summary
      pfam00001
      Location:41291
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31306
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      84564989..84565936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)