U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Gpbp1l1 GC-rich promoter binding protein 1-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 77110, updated on 28-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Gpbp1l1provided by MGI
    Official Full Name
    GC-rich promoter binding protein 1-like 1provided by MGI
    Primary source
    MGI:MGI:1924360
    See related
    Ensembl:ENSMUSG00000034042 AllianceGenome:MGI:1924360
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5330440M15Rik
    Summary
    Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human GPBP1L1 (GC-rich promoter binding protein 1 like 1). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 15.8), thymus adult (RPKM 14.8) and 28 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Gpbp1l1 in Genome Data Viewer
    Location:
    4 D1; 4 53.22 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116414357..116451099)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116557179..116593902)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116180277-116180386 Neighboring gene IAP promoted placental gene Neighboring gene STARR-seq mESC enhancer starr_11140 Neighboring gene transmembrane protein 69 Neighboring gene RIKEN cDNA C530005A16 gene Neighboring gene coiled-coil domain containing 17 Neighboring gene nuclear autoantigenic sperm protein (histone-binding) Neighboring gene STARR-positive B cell enhancer ABC_E4648 Neighboring gene STARR-positive B cell enhancer ABC_E4649 Neighboring gene STARR-positive B cell enhancer ABC_E7980

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. USP10 deubiquitinates Tau, mediating its aggregation. Wei Z, et al. Cell Death Dis, 2022 Aug 20. PMID 35987808, Free PMC Article
    2. Accelerating functional gene discovery in osteoarthritis. Butterfield NC, et al. Nat Commun, 2021 Jan 20. PMID 33473114, Free PMC Article
    3. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC8183

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    vasculin-like protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368177.1 → NP_001355106.1  vasculin-like protein 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK077148, AL669953, BC066034
      Consensus CDS
      CCDS18511.1
      UniProtKB/Swiss-Prot
      Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
      Related
      ENSMUSP00000102083.2, ENSMUST00000106475.2
      Conserved Domains (1) summary
      pfam15337
      Location:379 → 449
      Vasculin; Vascular protein family Vasculin-like 1

    2. NM_029868.4 → NP_084144.2  vasculin-like protein 1

      See identical proteins and their annotated locations for NP_084144.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AL669953
      Consensus CDS
      CCDS18511.1
      UniProtKB/Swiss-Prot
      Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
      Related
      ENSMUSP00000030460.9, ENSMUST00000030460.15
      Conserved Domains (1) summary
      pfam15337
      Location:379 → 449
      Vasculin; Vascular protein family Vasculin-like 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      116414357..116451099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320452.3 → XP_017175941.1  vasculin-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
      Conserved Domains (1) summary
      pfam15337
      Location:379 → 449
      Vasculin; Vascular protein family Vasculin-like 1

    2. XM_006503485.5 → XP_006503548.1  vasculin-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006503548.1

      UniProtKB/Swiss-Prot
      Q6NZP2, Q8BHW7, Q8BI03, Q8K2H8, Q9CTV6
      Conserved Domains (1) summary
      pfam15337
      Location:379 → 449
      Vasculin; Vascular protein family Vasculin-like 1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NZP2.1 GenPept UniProtKB/Swiss-Prot:Q6NZP2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools