FST follistatin [Gallus gallus (chicken)] - Gene

Summary

Symbol: FSTprovided by CGNC
Full Name: follistatinprovided by CGNC
Primary source: CGNC:11065
See related: Ensembl:ENSGALG00010012441
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (16612271..16618886)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (16612271..16618886)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network.
Title: The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network.
Suggest role for Follistatin in cardiac valvulogenesis in chick embryo.
Title: Patterns of expression of the Follistatin and Follistatin-like1 genes during chicken heart development: a potential role in valvulogenesis and late heart muscle cell formation.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables activin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of activin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of BMP signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: follistatin

Names: FS; activin-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205200.2 → NP_990531.1 follistatin precursor

See identical proteins and their annotated locations for NP_990531.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000089

UniProtKB/Swiss-Prot

Q90680, Q90844, Q9PS97

UniProtKB/TrEMBL

A0A089NA14

Conserved Domains (2) summary

smart00274
Location:166 → 189

FOLN; Follistatin-N-terminal domain-like

smart00280
Location:116 → 163

KAZAL; Kazal type serine protease inhibitors