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    CYP26A1 cytochrome P450 family 26 subfamily A member 1 [ Gallus gallus (chicken) ]

    Gene ID: 408183, updated on 10-Oct-2024

    Summary

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    Symbol
    CYP26A1provided by CGNC
    Full Name
    cytochrome P450 family 26 subfamily A member 1provided by CGNC
    Primary source
    CGNC:5082
    See related
    Ensembl:ENSGALG00010020413
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CYP26A
    Orthologs
    human mouse all
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    Genomic context

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    See CYP26A1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (21357933..21361343, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (21249280..21252691, complement)

    Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene myoferlin Neighboring gene uncharacterized LOC112532682 Neighboring gene uncharacterized LOC121111226 Neighboring gene cytochrome P450 family 26 subfamily C member 1 Neighboring gene exocyst complex component 6 Neighboring gene uncharacterized LOC107053706

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High levels of vitamin E affect retinol binding protein but not CYP26A1 in liver and hepatocytes from laying hens. Zhou XD, et al. Poult Sci, 2012 May. PMID 22499871
    2. Regulation of RALDH-1, RALDH-3 and CYP26A1 by transcription factors cVax/Vax2 and Tbx5 in the embryonic chick retina. Golz S, et al. Int J Dev Neurosci, 2008 Aug. PMID 18406560
    3. Complementary domains of retinoic acid production and degradation in the early chick embryo. Swindell EC, et al. Dev Biol, 1999 Dec 1. PMID 10588879
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CYP26A1 and its mRNA expression were not affected by vitamin E in both liver and hepatocytes.
      Title: High levels of vitamin E affect retinol binding protein but not CYP26A1 in liver and hepatocytes from laying hens.
    2. Results show that in the chick retina the compartmentalized expression of retinoic acid metabolizing enzymes RALDH-1, RALDH-3 and CYP26A1 requires the spatially restricted expression of the transcription factors cVax/Vax2 and Tbx5
      Title: Regulation of RALDH-1, RALDH-3 and CYP26A1 by transcription factors cVax/Vax2 and Tbx5 in the embryonic chick retina.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome P450 26A1
    Names
    cytochrome P450, family 26, subfamily A, polypeptide 1
    retinoic acid-degrading enzyme CYP26
    NP_001001129.2
    XP_015144084.1
    XP_046775919.1
    XP_046775920.1
    XP_046798728.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001129.2 → NP_001001129.2  cytochrome P450 26A1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000232
      UniProtKB/Swiss-Prot
      Q9PUB4, Q9PUG2
      Conserved Domains (1) summary
      cl12078
      Location:36 → 482
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      21357933..21361343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015288598.4 → XP_015144084.1  cytochrome P450 26A1 isoform X1

      UniProtKB/Swiss-Prot
      Q9PUB4, Q9PUG2
      UniProtKB/TrEMBL
      A0A8V0Z7G1
      Related
      ENSGALP00010029184.1, ENSGALT00010049370.1
      Conserved Domains (1) summary
      cl12078
      Location:36 → 445
      p450; Cytochrome P450

    2. XM_046942772.1 → XP_046798728.1  cytochrome P450 26A1 isoform X2

      Related
      ENSGALP00010029187.1, ENSGALT00010049377.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      21249280..21252691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046919963.1 → XP_046775919.1  cytochrome P450 26A1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z7G1

    2. XM_046919964.1 → XP_046775920.1  cytochrome P450 26A1 isoform X2

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9PUB4.1 GenPept UniProtKB/Swiss-Prot:Q9PUB4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials