NFAT5 nuclear factor of activated T-cells 5 [Gallus gallus (chicken)] - Gene

Summary

Symbol: NFAT5provided by CGNC
Full Name: nuclear factor of activated T-cells 5provided by CGNC
Primary source: CGNC:425
See related: Ensembl:ENSGALG00010008274
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: TonEBP
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	11	NC_052542.1 (18617410..18682760)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	11	NC_052583.1 (18965315..19030605)

Chromosome 11 - NC_052542.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The transcription factor TonEBP may be involved in the regulation of AVT genes expression in response to a hyperosmotic environment in chicken.
Title: TonEBP regulates hyperosmolality-induced arginine vasotocin gene expression in the chick (Gallus domesticus).

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription factor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in calcineurin-NFAT signaling cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytokine production	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of transcription regulator complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: nuclear factor of activated T-cells 5

Names: nuclear factor of activated T-cells 5, tonicity-responsive

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199000.3 → NP_001185929.2 nuclear factor of activated T-cells 5

Status: PROVISIONAL

Source sequence(s)

AB457023, JAENSK010000248

UniProtKB/TrEMBL

A0A8V0Y5J9

Related

ENSGALP00010011334.1, ENSGALT00010019786.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

18617410..18682760

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015292583.4 → XP_015148069.3 nuclear factor of activated T-cells 5 isoform X1

UniProtKB/TrEMBL

A0A8V0Y5J9

Conserved Domains (3) summary

cd07882
Location:280 → 440

RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)

PRK10263
Location:1132 → 1230

PRK10263; DNA translocase FtsK; Provisional

cl15674
Location:444 → 543

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
XM_015292587.3 → XP_015148073.2 nuclear factor of activated T-cells 5 isoform X3

UniProtKB/TrEMBL

B5BV17

Conserved Domains (3) summary

cd07882
Location:204 → 364

RHD-n_TonEBP; N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP)

PRK10263
Location:1056 → 1154

PRK10263; DNA translocase FtsK; Provisional

cl15674
Location:368 → 467

IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
XM_046899518.1 → XP_046755474.1 nuclear factor of activated T-cells 5 isoform X2

UniProtKB/TrEMBL

A0A8V0Y5J9
XM_046899519.1 → XP_046755475.1 nuclear factor of activated T-cells 5 isoform X4

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

18965315..19030605

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046925645.1 → XP_046781601.1 nuclear factor of activated T-cells 5 isoform X1

UniProtKB/TrEMBL

A0A8V0Y5J9
XM_046925647.1 → XP_046781603.1 nuclear factor of activated T-cells 5 isoform X3

UniProtKB/TrEMBL

B5BV17
XM_046925646.1 → XP_046781602.1 nuclear factor of activated T-cells 5 isoform X2

UniProtKB/TrEMBL

A0A8V0Y5J9
XM_046925648.1 → XP_046781604.1 nuclear factor of activated T-cells 5 isoform X4