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    URAH 5-hydroxyisourate hydrolase [ Gallus gallus (chicken) ]

    Gene ID: 415859, updated on 17-Aug-2024

    Summary

    Symbol
    URAHprovided by CGNC
    Full Name
    5-hydroxyisourate hydrolaseprovided by CGNC
    Primary source
    CGNC:50101
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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    Genomic context

    See URAH in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (18508353..18509994, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (18856342..18857983, complement)

    Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene dysbindin (dystrobrevin binding protein 1) domain containing 1 Neighboring gene growth arrest specific 8 Neighboring gene cadherin 3 Neighboring gene cadherin 1

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    5-hydroxyisourate hydrolase
    NP_001294879.2
    XP_004944388.2
    XP_025009963.2
    XP_040563045.1
    XP_046755471.1
    XP_046755472.1
    XP_046781594.1
    XP_046781595.1
    XP_046781596.1
    XP_046781597.1
    XP_046781598.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001307950.2NP_001294879.2  5-hydroxyisourate hydrolase

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000248
      Conserved Domains (1) summary
      cd05822
      Location:15127
      TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      18508353..18509994 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040707111.2XP_040563045.1  5-hydroxyisourate hydrolase isoform X5

      Conserved Domains (1) summary
      cd05822
      Location:12124
      TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...
    2. XM_046899516.1XP_046755472.1  5-hydroxyisourate hydrolase isoform X4

    3. XM_046899515.1XP_046755471.1  5-hydroxyisourate hydrolase isoform X3

    4. XM_004944331.5XP_004944388.2  5-hydroxyisourate hydrolase isoform X2

      Conserved Domains (1) summary
      cd05822
      Location:42154
      TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...
    5. XM_025154195.3XP_025009963.2  5-hydroxyisourate hydrolase isoform X1

      Conserved Domains (1) summary
      cd05822
      Location:42163
      TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      18856342..18857983 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046925642.1XP_046781598.1  5-hydroxyisourate hydrolase isoform X5

    2. XM_046925641.1XP_046781597.1  5-hydroxyisourate hydrolase isoform X4

    3. XM_046925640.1XP_046781596.1  5-hydroxyisourate hydrolase isoform X3

    4. XM_046925639.1XP_046781595.1  5-hydroxyisourate hydrolase isoform X2

    5. XM_046925638.1XP_046781594.1  5-hydroxyisourate hydrolase isoform X1