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    Nmur2 neuromedin U receptor 2 [ Mus musculus (house mouse) ]

    Gene ID: 216749, updated on 2-Nov-2024

    Summary

    Official Symbol
    Nmur2provided by MGI
    Official Full Name
    neuromedin U receptor 2provided by MGI
    Primary source
    MGI:MGI:2441765
    See related
    Ensembl:ENSMUSG00000037393 AllianceGenome:MGI:2441765
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nmu2r
    Summary
    Enables neuropeptide receptor activity. Acts upstream of or within several processes, including grooming behavior; neuropeptide signaling pathway; and reduction of food intake in response to dietary excess. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human NMUR2 (neuromedin U receptor 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in ovary adult (RPKM 1.4), subcutaneous fat pad adult (RPKM 1.0) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Nmur2 in Genome Data Viewer
    Location:
    11 B1.3; 11 33.39 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (55915816..55931813, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (56024990..56040987, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12236 Neighboring gene STARR-seq mESC enhancer starr_29547 Neighboring gene glycine receptor, alpha 1 subunit Neighboring gene STARR-seq mESC enhancer starr_29550 Neighboring gene STARR-seq mESC enhancer starr_29551 Neighboring gene STARR-seq mESC enhancer starr_29552 Neighboring gene STARR-seq mESC enhancer starr_29553 Neighboring gene predicted gene, 50502 Neighboring gene STARR-seq mESC enhancer starr_29554 Neighboring gene predicted gene 12239 Neighboring gene STARR-seq mESC enhancer starr_29558 Neighboring gene predicted gene, 46260 Neighboring gene predicted gene 12240 Neighboring gene predicted gene, 24253

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables intracellularly calcium-gated chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables intracellularly calcium-gated chloride channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables neuromedin U binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables neuromedin U binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables neuromedin U receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables neuromedin U receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables neuropeptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables neuropeptide receptor activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables neuropeptide receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in membrane IC
    Inferred by Curator
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    neuromedin-U receptor 2
    Names
    NMU-R2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153079.4NP_694719.2  neuromedin-U receptor 2

      See identical proteins and their annotated locations for NP_694719.2

      Status: PROVISIONAL

      Source sequence(s)
      AL671969
      Consensus CDS
      CCDS24716.1
      UniProtKB/Swiss-Prot
      Q8BZ39, Q91Z76
      UniProtKB/TrEMBL
      B2RPU9
      Related
      ENSMUSP00000044718.3, ENSMUST00000037682.3
      Conserved Domains (2) summary
      pfam00001
      Location:54319
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:48333
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      55915816..55931813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)