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    Ms4a8a membrane-spanning 4-domains, subfamily A, member 8A [ Mus musculus (house mouse) ]

    Gene ID: 64381, updated on 2-Nov-2024

    Summary

    Official Symbol
    Ms4a8aprovided by MGI
    Official Full Name
    membrane-spanning 4-domains, subfamily A, member 8Aprovided by MGI
    Primary source
    MGI:MGI:1927657
    See related
    Ensembl:ENSMUSG00000024730 AllianceGenome:MGI:1927657
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ms4a8; CD20L5; 2010004L09Rik
    Summary
    Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in rectum and stomach. Orthologous to human MS4A8 (membrane spanning 4-domains A8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in colon adult (RPKM 248.0), large intestine adult (RPKM 219.6) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ms4a8a in Genome Data Viewer
    Location:
    19 A; 19 7.62 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11044835..11058467, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11067471..11081103, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene 28347 Neighboring gene expressed sequence AW112010 Neighboring gene STARR-seq mESC enhancer starr_45564 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 pseudogene Neighboring gene membrane-spanning 4-domains, subfamily A, member 20 Neighboring gene NS1-associated protein 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    membrane-spanning 4-domains subfamily A member 8
    Names
    CD20 antigen-like 5
    MS4a8B protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022430.2NP_071875.2  membrane-spanning 4-domains subfamily A member 8

      See identical proteins and their annotated locations for NP_071875.2

      Status: VALIDATED

      Source sequence(s)
      AB026044, AK008099, CV305829
      Consensus CDS
      CCDS37921.1
      UniProtKB/Swiss-Prot
      F8WIR2, Q2TVW6, Q3T990, Q8CG94, Q99N10, Q9EQZ0
      Related
      ENSMUSP00000025636.7, ENSMUST00000025636.8
      Conserved Domains (1) summary
      pfam04103
      Location:109247
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      11044835..11058467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)