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    vars1.S valyl-tRNA synthetase 1 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 495303, updated on 18-Sep-2024

    Summary

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    Official Symbol
    vars1.S
    Official Full Name
    valyl-tRNA synthetase 1 S homeolog
    Primary source
    Xenbase:XB-GENE-865697
    Locus tag
    XELAEV_18042470mg
    See related
    EnsemblRapid:ENSXLAG00005009572
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    G7A; vars; vars2; vars.S
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See vars1.S in Genome Data Viewer
    Location:
    chromosome: 8S
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (82019545..82048834, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (79635360..79664722, complement)

    Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene chloride intracellular channel 1 S homeolog Neighboring gene DDAH family member 2, ADMA-independent S homeolog Neighboring gene heat shock 70 kDa protein-like Neighboring gene LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation. Gao Y, et al. J Biol Chem, 2014 Dec 26. PMID 25258324, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aminoacyl-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables valine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within valyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    valyl-tRNA synthetase
    Names
    valyl-tRNA synthetase S homeolog
    NP_001088439.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001094970.1 → NP_001088439.1  valyl-tRNA synthetase

      See identical proteins and their annotated locations for NP_001088439.1

      Status: PROVISIONAL

      Source sequence(s)
      BC084762
      UniProtKB/TrEMBL
      A0A974H617, Q5U5C2
      Related
      ENSXLAP00005028022.1, ENSXLAT00005028759.1
      Conserved Domains (6) summary
      cd07962
      Location:917 → 1054
      Anticodon_Ia_Val; Anticodon-binding domain of valyl tRNA synthetases
      cd00817
      Location:316 → 917
      ValRS_core; catalytic core domain of valyl-tRNA synthetases
      PTZ00419
      Location:263 → 1242
      PTZ00419; valyl-tRNA synthetase-like protein; Provisional
      pfam10458
      Location:1175 → 1235
      Val_tRNA-synt_C; Valyl tRNA synthetase tRNA binding arm
      pfam13603
      Location:490 → 619
      tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
      cl02776
      Location:79 → 192
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      82019545..82048834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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