U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ppp1r37 protein phosphatase 1, regulatory subunit 37 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308398, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Symbol
    Ppp1r37provided by RGD
    Full Name
    protein phosphatase 1, regulatory subunit 37provided by RGD
    Primary source
    RGD:1595870
    See related
    EnsemblRapid:ENSRNOG00000017692 AllianceGenome:RGD:1595870
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lrrc68
    Summary
    Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of catalytic activity. Orthologous to human PPP1R37 (protein phosphatase 1 regulatory subunit 37). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 123.7), Brain (RPKM 118.8) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Ppp1r37 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88308782..88340796, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79180794..79212612, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80439718..80471527, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 6A Neighboring gene NTPase, KAP family P-loop domain containing 1 Neighboring gene gem (nuclear organelle) associated protein 7 Neighboring gene zinc finger protein 296

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Docking motif-guided mapping of the interactome of protein phosphatase-1. Hendrickx A, et al. Chem Biol, 2009 Apr 24. PMID 19389623
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein phosphatase 1 regulatory subunit 37
    Names
    leucine rich repeat containing 68
    leucine-rich repeat-containing protein 68

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107482.1 → NP_001100952.1  protein phosphatase 1 regulatory subunit 37

      See identical proteins and their annotated locations for NP_001100952.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473979
      UniProtKB/Swiss-Prot
      B2RYF1
      UniProtKB/TrEMBL
      A0A8I6GE78
      Related
      ENSRNOP00000023866.5, ENSRNOT00000023867.8
      Conserved Domains (3) summary
      COG4886
      Location:248 → 453
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00116
      Location:115 → 433
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:168 → 196
      LRR_RI; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      88308782..88340796 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261305.1 → XP_063117375.1  protein phosphatase 1 regulatory subunit 37 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B2RYF1.1 GenPept UniProtKB/Swiss-Prot:B2RYF1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools