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    Tpbgl trophoblast glycoprotein-like [ Mus musculus (house mouse) ]

    Gene ID: 100503386, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tpbglprovided by MGI
    Official Full Name
    trophoblast glycoprotein-likeprovided by MGI
    Primary source
    MGI:MGI:3646425
    See related
    Ensembl:ENSMUSG00000096606 AllianceGenome:MGI:3646425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm4980; EG245190
    Summary
    Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TPBGL (trophoblast glycoprotein like). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human all
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    Genomic context

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    See Tpbgl in Genome Data Viewer
    Location:
    7 E1; 7 54.11 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99273274..99276310, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (99624067..99627103, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19659 Neighboring gene predicted gene, 40450 Neighboring gene predicted gene, 34172 Neighboring gene arrestin, beta 1 Neighboring gene microRNA 326 Neighboring gene predicted gene, 53384 Neighboring gene predicted gene, 25409

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • 6430704N06

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in negative regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    trophoblast glycoprotein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195529.1 → NP_001182458.1  trophoblast glycoprotein-like precursor

      See identical proteins and their annotated locations for NP_001182458.1

      Status: VALIDATED

      Source sequence(s)
      AC111086, AK032609
      Consensus CDS
      CCDS57566.1
      UniProtKB/Swiss-Prot
      Q8C013
      Related
      ENSMUSP00000137154.2, ENSMUST00000178124.3
      Conserved Domains (3) summary
      smart00082
      Location:236 → 288
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:98 → 121
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:96 → 153
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      99273274..99276310 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C013.2 GenPept UniProtKB/Swiss-Prot:Q8C013

    Gene LinkOut

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