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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853944, updated on 2-Nov-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000001778
    Locus tag
    YKR070W
    See related
    AllianceGenome:SGD:S000001778; FungiDB:YKR070W; VEuPathDB:YKR070W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable hydrolase activity. Predicted to be involved in glycerophospholipid biosynthetic process. Located in mitochondrion. Orthologous to human HDHD5 (haloacid dehalogenase like hydrolase domain containing 5). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (573574..574632)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene TRAPP complex core subunit BET3 Neighboring gene uroporphyrinogen-III C-methyltransferase Neighboring gene electron carrier DRE2 Neighboring gene phosphopantothenoylcysteine decarboxylase complex subunit SIS2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS. Kuznetsova E, et al. J Biol Chem, 2015 Jul 24. PMID 26071590, Free PMC Article
    2. Ribosome-Associated Mba1 Escorts Cox2 from Insertion Machinery to Maturing Assembly Intermediates. Lorenzi I, et al. Mol Cell Biol, 2016 Nov 15. PMID 27550809, Free PMC Article
    3. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765
    4. Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation. Pereira F, et al. PLoS One, 2019. PMID 30682149, Free PMC Article
    5. Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae. Renvoisé M, et al. J Proteomics, 2014 Jun 25. PMID 24769239

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in glycerophospholipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_012996.1
    • hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      573574..574632
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179860.1 → NP_012996.1  TPA: uncharacterized protein YKR070W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012996.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXD1, P36151
      UniProtKB/TrEMBL
      A7A030, B3LRE4, B5VML7, C7GX70, C8ZCN2, G2WI98, N1P0Z3
      Conserved Domains (1) summary
      TIGR01456
      Location:14 → 348
      CECR5; HAD-superfamily class IIA hydrolase, TIGR01456, CECR5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36151.1

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