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    YUR1 mannosyltransferase YUR1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853302, updated on 2-Nov-2024

    Summary

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    Official Symbol
    YUR1
    Official Full Name
    mannosyltransferase YUR1
    Primary source
    SGD:S000003675
    Locus tag
    YJL139C
    See related
    AllianceGenome:SGD:S000003675; FungiDB:YJL139C; VEuPathDB:YJL139C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables mannosyltransferase activity. Involved in cell wall mannoprotein biosynthetic process and protein N-linked glycosylation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See YUR1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (151713..152999, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Irc9p Neighboring gene serine/threonine protein kinase YAK1 Neighboring gene DNA-directed RNA polymerase II subunit RPB4 Neighboring gene translation initiation factor eIF4A Neighboring gene glycogenin glucosyltransferase GLG2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Hill K, et al. Genetics, 1992 Feb. PMID 1541391, Free PMC Article
    2. Adaptive evolution of nontransitive fitness in yeast. Buskirk SW, et al. Elife, 2020 Dec 29. PMID 33372653, Free PMC Article
    3. Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. Lussier M, et al. J Biol Chem, 1996 May 3. PMID 8631921
    4. Biosynthesis of the side chain of yeast glycosylphosphatidylinositol anchors is operated by novel mannosyltransferases located in the endoplasmic reticulum and the Golgi apparatus. Sipos G, et al. J Biol Chem, 1995 Aug 25. PMID 7649981
    5. Sequence analysis of a 40.7 kb segment from the left arm of yeast chromosome X reveals 14 known genes and 13 new open reading frames including homologues of genes clustered on the right arm of chromosome XI. Katsoulou C, et al. Yeast, 1996 Jun 30. PMID 8813765

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables alpha-1,2-mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mannosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall mannoprotein biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell wall mannoprotein biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mannosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein N-linked glycosylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mannosyltransferase YUR1
    NP_012396.1
    • Mannosyltransferase involved in protein N-glycosylation; member of the KTR1 family; located in the Golgi apparatus; YUR1 has a paralog, KTR2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      151713..152999 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181572.1 → NP_012396.1  TPA: mannosyltransferase YUR1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012396.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW45, P26725
      UniProtKB/TrEMBL
      A6ZQJ0, B3LPX9, B5VL40, C8ZB78, G2WGN1, N1P1H5
      Conserved Domains (1) summary
      COG5020
      Location:7 → 424
      KTR1; Mannosyltransferase [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26725.1

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