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    LINC02273 long intergenic non-protein coding RNA 2273 [ Homo sapiens (human) ]

    Gene ID: 100996286, updated on 22-Oct-2024

    Summary

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    Official Symbol
    LINC02273provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2273provided by HGNC
    Primary source
    HGNC:HGNC:53188
    See related
    Ensembl:ENSG00000245954 AllianceGenome:HGNC:53188
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in lymph node (RPKM 3.2), appendix (RPKM 1.5) and 5 other tissues See more
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    Genomic context

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    See LINC02273 in Genome Data Viewer
    Location:
    4q31.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (152100753..152104720)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (155423860..155427846)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (153021905..153025872)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 3074 Neighboring gene RNA, 5S ribosomal pseudogene 169 Neighboring gene NANOG hESC enhancer GRCh37_chr4:152925827-152926328 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22025 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:152945037-152945536 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15749 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22026 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22027 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22028 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:153021562-153022062 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:153022063-153022563 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:153022858-153024057 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:153027165-153028364 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15750 Neighboring gene uncharacterized LOC124900800 Neighboring gene uncharacterized LOC105377489

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription. Xiu B, et al. Mol Cancer, 2019 Dec 19. PMID 31856843, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_121627.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC079340
      Related
      ENST00000499452.3

    2. NR_121628.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' terminal exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      BC040914, BU617226, CB986668
      Related
      ENST00000509332.8

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      152100753..152104720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      155423860..155427846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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