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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001278919.2 → NP_001265848.1 voltage-gated inwardly rectifying potassium channel KCNH6 isoform 3
See identical proteins and their annotated locations for NP_001265848.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 3, which is shorter, compared to isoform 1.
- Source sequence(s)
-
AA825356, AK090969, AK296498, BE465143, BM561167, CD632730, DB147394, DB506421
- Consensus CDS
-
CCDS62290.1
- UniProtKB/Swiss-Prot
- J9JID4, Q9BRD7, Q9H252
- UniProtKB/TrEMBL
-
B4DKC0
- Related
- ENSP00000318212.5, ENST00000314672.10
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
NM_001278920.2 → NP_001265849.1 voltage-gated inwardly rectifying potassium channel KCNH6 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and 5' coding region, uses a downstream start codon, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (4) has a shorter N-terminus and is shorter, compared to isoform 1.
- Source sequence(s)
-
AA825356, AK090969, AK298363, BE465143, CD632730, DB506421
- UniProtKB/TrEMBL
-
B4DPJ3
- Conserved Domains (4) summary
-
- COG0664
Location:465 → 581
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:471 → 582
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- pfam00520
Location:173 → 397
- Ion_trans; Ion transport protein
- pfam07885
Location:340 → 394
- Ion_trans_2; Ion channel
-
NM_030779.4 → NP_110406.1 voltage-gated inwardly rectifying potassium channel KCNH6 isoform 1
See identical proteins and their annotated locations for NP_110406.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AA825356, AF311913, BE465143, CD632730, DB147394, DB506421
- Consensus CDS
-
CCDS11638.1
- UniProtKB/TrEMBL
-
B4DKC0
- Related
- ENSP00000463533.1, ENST00000583023.1
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
NM_173092.4 → NP_775115.1 voltage-gated inwardly rectifying potassium channel KCNH6 isoform 2
See identical proteins and their annotated locations for NP_775115.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame segment and an alternate in-frame exon but includes an alternate 3' terminal exon with an alternate 3' UTR, compared to variant 1. It encodes isoform 2, which is shorter, compared to isoform 1.
- Source sequence(s)
-
AC113554, AK091877, CD632730
- Consensus CDS
-
CCDS11639.1
- UniProtKB/TrEMBL
-
B4DKC0
- Related
- ENSP00000463830.1, ENST00000581784.5
- Conserved Domains (6) summary
-
- COG0664
Location:535 → 651
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:541 → 652
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 467
- Ion_trans; Ion transport protein
- pfam07885
Location:393 → 464
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p14 Primary Assembly
- Range
-
63523358..63548992
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017025175.2 → XP_016880664.1 potassium voltage-gated channel subfamily H member 6 isoform X1
- UniProtKB/TrEMBL
-
B4DKC0
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
XM_017025177.2 → XP_016880666.1 potassium voltage-gated channel subfamily H member 6 isoform X3
- UniProtKB/Swiss-Prot
- J9JID4, Q9BRD7, Q9H252
- UniProtKB/TrEMBL
-
B4DKC0
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
XM_047436856.1 → XP_047292812.1 potassium voltage-gated channel subfamily H member 6 isoform X11
-
XM_017025176.3 → XP_016880665.1 potassium voltage-gated channel subfamily H member 6 isoform X2
- UniProtKB/TrEMBL
-
B4DKC0
-
XM_017025178.3 → XP_016880667.1 potassium voltage-gated channel subfamily H member 6 isoform X4
- UniProtKB/TrEMBL
-
B4DKC0
-
XM_017025179.3 → XP_016880668.1 potassium voltage-gated channel subfamily H member 6 isoform X5
- UniProtKB/TrEMBL
-
B4DKC0
-
XM_011525310.3 → XP_011523612.1 potassium voltage-gated channel subfamily H member 6 isoform X9
See identical proteins and their annotated locations for XP_011523612.1
- UniProtKB/TrEMBL
-
B4DKC0
- Related
- ENSP00000396900.2, ENST00000456941.6
- Conserved Domains (6) summary
-
- COG0664
Location:535 → 651
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:541 → 652
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 467
- Ion_trans; Ion transport protein
- pfam07885
Location:393 → 464
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
XM_047436854.1 → XP_047292810.1 potassium voltage-gated channel subfamily H member 6 isoform X6
-
XM_047436855.1 → XP_047292811.1 potassium voltage-gated channel subfamily H member 6 isoform X10
-
XM_017025180.3 → XP_016880669.1 potassium voltage-gated channel subfamily H member 6 isoform X12
- UniProtKB/TrEMBL
-
B4DPJ3
-
XM_011525309.3 → XP_011523611.1 potassium voltage-gated channel subfamily H member 6 isoform X8
- UniProtKB/TrEMBL
-
B4DKC0
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
XM_011525308.3 → XP_011523610.1 potassium voltage-gated channel subfamily H member 6 isoform X7
- UniProtKB/TrEMBL
-
B4DKC0
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
XM_011525311.2 → XP_011523613.1 potassium voltage-gated channel subfamily H member 6 isoform X13
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 724
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
XM_011525312.2 → XP_011523614.1 potassium voltage-gated channel subfamily H member 6 isoform X14
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
-
XM_011525313.2 → XP_011523615.1 potassium voltage-gated channel subfamily H member 6 isoform X15
- Conserved Domains (6) summary
-
- COG0664
Location:588 → 704
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:594 → 705
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:41 → 132
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:296 → 520
- Ion_trans; Ion transport protein
- pfam07885
Location:463 → 517
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 132
- PAS_9; PAS domain
RNA
-
XR_934568.2 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060941.1 Alternate T2T-CHM13v2.0
- Range
-
64393673..64419606
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054317425.1 → XP_054173400.1 potassium voltage-gated channel subfamily H member 6 isoform X1
-
XM_054317427.1 → XP_054173402.1 potassium voltage-gated channel subfamily H member 6 isoform X3
-
XM_054317426.1 → XP_054173401.1 potassium voltage-gated channel subfamily H member 6 isoform X2
-
XM_054317428.1 → XP_054173403.1 potassium voltage-gated channel subfamily H member 6 isoform X4
-
XM_054317429.1 → XP_054173404.1 potassium voltage-gated channel subfamily H member 6 isoform X5
-
XM_054317433.1 → XP_054173408.1 potassium voltage-gated channel subfamily H member 6 isoform X9
-
XM_054317430.1 → XP_054173405.1 potassium voltage-gated channel subfamily H member 6 isoform X6
-
XM_054317434.1 → XP_054173409.1 potassium voltage-gated channel subfamily H member 6 isoform X10
-
XM_054317436.1 → XP_054173411.1 potassium voltage-gated channel subfamily H member 6 isoform X12
-
XM_054317435.1 → XP_054173410.1 potassium voltage-gated channel subfamily H member 6 isoform X11
-
XM_054317432.1 → XP_054173407.1 potassium voltage-gated channel subfamily H member 6 isoform X8
-
XM_054317431.1 → XP_054173406.1 potassium voltage-gated channel subfamily H member 6 isoform X7
-
XM_054317437.1 → XP_054173412.1 potassium voltage-gated channel subfamily H member 6 isoform X13
-
XM_054317438.1 → XP_054173413.1 potassium voltage-gated channel subfamily H member 6 isoform X14
-
XM_054317439.1 → XP_054173414.1 potassium voltage-gated channel subfamily H member 6 isoform X15
RNA
-
XR_008484947.1 RNA Sequence