1700013H16Rik RIKEN cDNA 1700013H16 gene [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: 1700013H16Rikprovided by MGI
Official Full Name: RIKEN cDNA 1700013H16 geneprovided by MGI
Primary source: MGI:MGI:1922764
See related: Ensembl:ENSMUSG00000054727 AllianceGenome:MGI:1922764
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Slx2; Xlr6
Summary: Predicted to be involved in meiotic cell cycle and spermatid development. Located in XY body; chromatin; and nucleolus. Is expressed in gonad. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward testis adult (RPKM 1.5) See more
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Genomic context

Location:: X A5; X 30.01 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (52744868..52759936, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (53742901..53757970, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Trim27 connecting Slx2 may regulate meiotic processes in multiple ways by influencing XY body formation and germ cell proliferation during spermatogenesis.
Title: Trim27 interacts with Slx2, is associated with meiotic processes during spermatogenesis.
SLX2 might be a novel gametogenesis-related protein that could play multiple roles in regulation of meiotic processes including synaptonemal complex assembly and chromosome segregation.
Title: SLX2 interacting with BLOS2 is differentially expressed during mouse oocyte meiotic maturation.
SLX2 interacts with synaptonemal complex central element protein 2 (SYCE2), an important component of synaptonemal complex.
Title: SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.
accumulates at the XY body of early pachytene to midpachytene spermatocytes
Title: Characterization of a novel mouse gene encoding an SYCP3-like protein that relocalizes from the XY body to the nucleolus during prophase of male meiosis I.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in meiotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in spermatid development	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in XY body	IDA Inferred from Direct Assay more info	PubMed
located_in chromatin	IDA Inferred from Direct Assay more info	PubMed
located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in synaptonemal complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: synaptonemal complex protein 3-like

Names: SYCP3-like X-linked 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001200013.1 → NP_001186942.1 synaptonemal complex protein 3-like

See identical proteins and their annotated locations for NP_001186942.1

Status: VALIDATED

Source sequence(s)

AK005953, AL691513

Consensus CDS

CCDS53071.1

UniProtKB/TrEMBL

Q9DAC5

Related

ENSMUSP00000063474.3, ENSMUST00000067940.3

Conserved Domains (2) summary

pfam04803
Location:151 → 270

Cor1; Cor1/Xlr/Xmr conserved region

pfam15724
Location:4 → 69

TMEM119; TMEM119 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000086.8 Reference GRCm39 C57BL/6J

Range

52744868..52759936 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006535361.4 → XP_006535424.1 synaptonemal complex protein 3-like isoform X1

Conserved Domains (1) summary

pfam04803
Location:11 → 142

Cor1; Cor1/Xlr/Xmr conserved region