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    CG5715 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42895, updated on 22-Aug-2024

    Summary

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    Official Symbol
    CG5715provided by FlyBase
    Primary source
    FLYBASE:FBgn0039180
    Locus tag
    Dmel_CG5715
    See related
    AllianceGenome:FB:FBgn0039180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5715
    Summary
    Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Is expressed in organism. Orthologous to human ASTL (astacin like metalloendopeptidase). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG5715 in Genome Data Viewer
    Location:
    95F10-95F10; 3-84 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24293366..24294399, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20119088..20120121, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45662 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Uridine-cytidine kinase Neighboring gene crumbs Neighboring gene Nuclear polyadenosine RNA-binding 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Severe Fertility Effects of sheepish Sperm Caused by Failure To Enter Female Sperm Storage Organs in Drosophila melanogaster. Tomaru M, et al. G3 (Bethesda), 2018 Jan 4. PMID 29158336, Free PMC Article
    2. A genetic in vivo system to detect asymmetrically distributed RNA. JayaNandanan N, et al. EMBO Rep, 2011 Oct 28. PMID 21921935, Free PMC Article
    3. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044, Free PMC Article
    4. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5715-PA
    NP_651242.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      24293366..24294399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142985.4 → NP_651242.1  uncharacterized protein Dmel_CG5715 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651242.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1EC99, Q9VC98
      Related
      FBpp0084018
      Conserved Domains (2) summary
      cd04280
      Location:107 → 291
      ZnMc_astacin_like; Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to ...
      pfam01400
      Location:104 → 295
      Astacin; Astacin (Peptidase family M12A)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VC98 Q9VC98

    Gene LinkOut

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