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    npy8br neuropeptide Y receptor Y8b [ Danio rerio (zebrafish) ]

    Gene ID: 30713, updated on 28-Oct-2024

    Summary

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    Official Symbol
    npy8brprovided by ZNC
    Official Full Name
    neuropeptide Y receptor Y8bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-980526-208
    See related
    Ensembl:ENSDARG00000005780 AllianceGenome:ZFIN:ZDB-GENE-980526-208
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zyb; npyryb; zgc:194624; zgc:194648
    Summary
    Enables neuropeptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Is expressed in several structures, including brain; digestive system; hatching gland; immune system; and otic vesicle. [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    all
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    Genomic context

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    See npy8br in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (51629197..51661952, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (51648181..51675535, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 39 Neighboring gene potassium channel tetramerization domain containing 9a Neighboring gene kelch-like family member 22 Neighboring gene T-box transcription factor 16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Neuropeptide Y receptor subtype with unique properties cloned in the zebrafish: the zYa receptor. Starbäck P, et al. Brain Res Mol Brain Res, 1999 Jul 5. PMID 10407172
    2. Cloning of a neuropeptide Y/peptide YY receptor from the Atlantic cod: the Yb receptor. Arvidsson AK, et al. Regul Pept, 1998 Sep 25. PMID 9802392
    3. Binding properties of three neuropeptide Y receptor subtypes from zebrafish: comparison with mammalian Y1 receptors. Berglund MM, et al. Biochem Pharmacol, 2000 Dec 15. PMID 11108796
    4. Cloning, pharmacology, and distribution of the neuropeptide Y-receptor Yb in rainbow trout. Larson ET, et al. Peptides, 2003 Mar. PMID 12732336
    5. Novel neuropeptide Y Y2-like receptor subtype in zebrafish and frogs supports early vertebrate chromosome duplications. Fredriksson R, et al. J Mol Evol, 2004 Jan. PMID 14743318

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Neuropeptide Y rceptors zYb and zYc are expressed during ontogeny.
      Title: Developmental expression of NPY/PYY receptors zYb and zYc in zebrafish.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neuropeptide Y receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neuropeptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables neuropeptide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables neuropeptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    neuropeptide Y receptor Y8b
    Names
    neuropeptide Y/peptide YY receptor YB

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131436.1 → NP_571511.1  neuropeptide Y receptor Y8b

      See identical proteins and their annotated locations for NP_571511.1

      Status: PROVISIONAL

      Source sequence(s)
      AF030245
      UniProtKB/TrEMBL
      B3DHJ7, O57463
      Related
      ENSDARP00000013426.5, ENSDART00000015833.7
      Conserved Domains (2) summary
      pfam00001
      Location:42 → 308
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:38 → 162
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      51629197..51661952 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009304308.4 → XP_009302583.1  neuropeptide Y receptor Y8b isoform X1

      See identical proteins and their annotated locations for XP_009302583.1

      UniProtKB/TrEMBL
      B3DHJ7, O57463
      Conserved Domains (2) summary
      pfam00001
      Location:42 → 308
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:38 → 162
      7tm_4; Olfactory receptor
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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