ces2a carboxylesterase 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ces2aprovided by ZNC
Official Full Name: carboxylesterase 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061013-99
See related: Ensembl:ENSDARG00000041569 AllianceGenome:ZFIN:ZDB-GENE-061013-99
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cbe; ces2; im:6908784; zgc:153863; si:dkey-38l12.2
Summary: Predicted to enable carboxylic ester hydrolase activity. Is expressed in liver; pectoral fin; pleuroperitoneal region; yolk; and yolk syncytial layer. Orthologous to human CES2 (carboxylesterase 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 18

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (17408480..17415597, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (17419414..17426531, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb58f03.x1 (e-PCR)
- UniSTS:190815

fb66e04 (e-PCR)
- UniSTS:187333

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables carboxylic ester hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

General protein information

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Preferred Names: carboxylesterase 2a

Names: carboxylesterase 2 (intestine, liver)

NP_001070720.1

EC 3.1.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077252.1 → NP_001070720.1 carboxylesterase 2a precursor

See identical proteins and their annotated locations for NP_001070720.1

Status: PROVISIONAL

Source sequence(s)

BC124754

UniProtKB/TrEMBL

Q08BF1

Related

ENSDARP00000090963.4, ENSDART00000100190.6

Conserved Domains (2) summary

COG0657
Location:122 → 346

Aes; Acetyl esterase/lipase [Lipid transport and metabolism]

pfam00135
Location:21 → 541

COesterase; Carboxylesterase family