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    FBXW7 F-box and WD repeat domain containing 7 [ Canis lupus familiaris (dog) ]

    Gene ID: 475465, updated on 17-Aug-2024

    Summary

    Official Symbol
    FBXW7provided by VGNC
    Official Full Name
    F-box and WD repeat domain containing 7provided by VGNC
    Primary source
    VGNC:VGNC:40797
    See related
    Ensembl:ENSCAFG00845007020
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See FBXW7 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (50869433..51101086, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (50529850..50761421, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (50542860..50774097, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (50130239..50363954, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (50231872..50463188, complement)

    Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090094 Neighboring gene uncharacterized LOC119868714 Neighboring gene U6 spliceosomal RNA Neighboring gene short coiled-coil protein Neighboring gene uncharacterized LOC111090096 Neighboring gene uncharacterized LOC119869289

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in ubiquitin recycling IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    F-box/WD repeat-containing protein 7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051819.1 Reference ROS_Cfam_1.0

      Range
      50869433..51101086 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038688632.1XP_038544560.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSD7, A0A8C0MVQ8, A0A8C0S7B0, A0A8I3N0Z3
      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    2. XM_038688633.1XP_038544561.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSD7, A0A8C0MVQ8, A0A8C0S7B0, A0A8I3N0Z3
      Related
      ENSCAFP00845009912.1, ENSCAFT00845012707.1
      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    3. XM_038688635.1XP_038544563.1  F-box/WD repeat-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A8C0S7D9, A0A8I3N229
      Related
      ENSCAFP00845009946.1, ENSCAFT00845012754.1
      Conserved Domains (3) summary
      cd00200
      Location:256532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:266301
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:163207
      F-box-like
    4. XM_038688634.1XP_038544562.1  F-box/WD repeat-containing protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LM89, A0A8C0N3B2, A0A8I3N148
      Related
      ENSCAFP00845009972.1, ENSCAFT00845012788.1
      Conserved Domains (3) summary
      cd00200
      Location:294570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:304339
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:201245
      F-box-like
    5. XM_038688636.1XP_038544564.1  F-box/WD repeat-containing protein 7 isoform X4

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049275.1 Alternate UMICH_Zoey_3.1

      Range
      50130239..50363954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038496633.1XP_038352561.1  F-box/WD repeat-containing protein 7 isoform X1

      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    2. XM_038496634.1XP_038352562.1  F-box/WD repeat-containing protein 7 isoform X1

      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    3. XM_038496636.1XP_038352564.1  F-box/WD repeat-containing protein 7 isoform X3

      Conserved Domains (3) summary
      cd00200
      Location:256532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:266301
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:163207
      F-box-like
    4. XM_038496635.1XP_038352563.1  F-box/WD repeat-containing protein 7 isoform X2

      Conserved Domains (3) summary
      cd00200
      Location:294570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:304339
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:201245
      F-box-like
    5. XM_038496637.1XP_038352565.1  F-box/WD repeat-containing protein 7 isoform X4

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

      Range
      50231872..50463188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038622960.1XP_038478888.1  F-box/WD repeat-containing protein 7 isoform X1

      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    2. XM_038622961.1XP_038478889.1  F-box/WD repeat-containing protein 7 isoform X1

      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    3. XM_038622963.1XP_038478891.1  F-box/WD repeat-containing protein 7 isoform X3

      Conserved Domains (3) summary
      cd00200
      Location:256532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:266301
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:163207
      F-box-like
    4. XM_038622962.1XP_038478890.1  F-box/WD repeat-containing protein 7 isoform X2

      Conserved Domains (3) summary
      cd00200
      Location:294570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:304339
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:201245
      F-box-like
    5. XM_038622964.1XP_038478892.1  F-box/WD repeat-containing protein 7 isoform X4

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

      Range
      50542860..50774097 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038559027.1XP_038414955.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSD7, A0A8C0MVQ8, A0A8C0S7B0, A0A8I3N0Z3
      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    2. XM_038559028.1XP_038414956.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSD7, A0A8C0MVQ8, A0A8C0S7B0, A0A8I3N0Z3
      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    3. XM_038559030.1XP_038414958.1  F-box/WD repeat-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A8C0S7D9, A0A8I3N229
      Conserved Domains (3) summary
      cd00200
      Location:256532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:266301
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:163207
      F-box-like
    4. XM_038559029.1XP_038414957.1  F-box/WD repeat-containing protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LM89, A0A8C0N3B2, A0A8I3N148
      Conserved Domains (3) summary
      cd00200
      Location:294570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:304339
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:201245
      F-box-like
    5. XM_038559031.1XP_038414959.1  F-box/WD repeat-containing protein 7 isoform X4

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      50529850..50761421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038449238.1XP_038305166.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSD7, A0A8C0MVQ8, A0A8C0S7B0, A0A8I3N0Z3
      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    2. XM_038449244.1XP_038305172.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LSD7, A0A8C0MVQ8, A0A8C0S7B0, A0A8I3N0Z3
      Conserved Domains (3) summary
      cd00200
      Location:379655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:389424
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:286330
      F-box-like
    3. XM_532689.7XP_532689.2  F-box/WD repeat-containing protein 7 isoform X3

      See identical proteins and their annotated locations for XP_532689.2

      UniProtKB/TrEMBL
      A0A8C0S7D9, A0A8I3N229
      Conserved Domains (3) summary
      cd00200
      Location:256532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:266301
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:163207
      F-box-like
    4. XM_848531.6XP_853624.1  F-box/WD repeat-containing protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LM89, A0A8C0N3B2, A0A8I3N148
      Conserved Domains (3) summary
      cd00200
      Location:294570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:304339
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:201245
      F-box-like
    5. XM_022403517.2XP_022259225.1  F-box/WD repeat-containing protein 7 isoform X4