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    HSPA8 heat shock protein family A (Hsp70) member 8 [ Canis lupus familiaris (dog) ]

    Gene ID: 479406, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HSPA8provided by VGNC
    Official Full Name
    heat shock protein family A (Hsp70) member 8provided by VGNC
    Primary source
    VGNC:VGNC:59028
    See related
    Ensembl:ENSCAFG00845012887
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See HSPA8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (11243037..11247671)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (11348073..11352702)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (11323539..11328166)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (11346458..11351078)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (11279270..11283884)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene CXADR like membrane protein Neighboring gene uncharacterized LOC106558786 Neighboring gene small nucleolar RNA SNORD14 Neighboring gene brain specific homeobox Neighboring gene junctional cadherin complex regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Light-activated BioID - an optically activated proximity labeling system to study protein-protein interactions. Shafraz O, et al. J Cell Sci, 2023 Oct 1. PMID 37756605, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables misfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to unfolded protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chaperone cofactor-dependent protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heat shock cognate 71 kDa protein
    XP_005619707.1
    XP_038330647.1
    XP_038391779.1
    XP_038455979.1
    XP_038520520.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      11243037..11247671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038664592.1 → XP_038520520.1  heat shock cognate 71 kDa protein

      UniProtKB/TrEMBL
      A0A8C0KB80, A0A8C0LZQ6, A0A8I3NK47, A0A8I3NNW3, A0A8P0TMD0
      Related
      ENSCAFP00845018012.1, ENSCAFT00845022977.1
      Conserved Domains (1) summary
      PTZ00009
      Location:1 → 613
      PTZ00009; heat shock 70 kDa protein; Provisional

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      11346458..11351078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038474719.1 → XP_038330647.1  heat shock cognate 71 kDa protein

      Conserved Domains (1) summary
      PTZ00009
      Location:1 → 613
      PTZ00009; heat shock 70 kDa protein; Provisional

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      11279270..11283884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038600051.1 → XP_038455979.1  heat shock cognate 71 kDa protein

      Conserved Domains (1) summary
      PTZ00009
      Location:1 → 613
      PTZ00009; heat shock 70 kDa protein; Provisional

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      11323539..11328166
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038535851.1 → XP_038391779.1  heat shock cognate 71 kDa protein

      UniProtKB/TrEMBL
      A0A8C0KB80, A0A8C0LZQ6, A0A8I3NK47, A0A8I3NNW3, A0A8P0TMD0
      Conserved Domains (1) summary
      PTZ00009
      Location:1 → 613
      PTZ00009; heat shock 70 kDa protein; Provisional

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      11348073..11352702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005619650.4 → XP_005619707.1  heat shock cognate 71 kDa protein

      See identical proteins and their annotated locations for XP_005619707.1

      UniProtKB/TrEMBL
      A0A8C0KB80, A0A8C0LZQ6, A0A8I3NK47, A0A8I3NNW3, A0A8P0TMD0
      Conserved Domains (1) summary
      PTZ00009
      Location:1 → 613
      PTZ00009; heat shock 70 kDa protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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