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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001271753.2 → NP_001258682.1 DNA (cytosine-5)-methyltransferase 3A isoform 1
See identical proteins and their annotated locations for NP_001258682.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1 and 3 encode the same isoform (1, also known as Dnmt3a1).
- Source sequence(s)
-
AC159324, CR974568
- Consensus CDS
-
CCDS36397.1
- UniProtKB/Swiss-Prot
- O88508, Q3TZK8, Q3UH24, Q8CJ60, Q922J0, Q9CSE1
- Related
- ENSMUSP00000134009.2, ENSMUST00000174817.8
- Conserved Domains (5) summary
-
- cd05835
Location:286 → 372
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- PTZ00449
Location:1 → 121
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- COG0270
Location:628 → 791
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- TIGR00927
Location:17 → 282
- 2A1904; K+-dependent Na+/Ca+ exchanger
- cd11729
Location:483 → 610
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
NM_001421857.1 → NP_001408786.1 DNA (cytosine-5)-methyltransferase 3A isoform 1
Status: VALIDATED
- Source sequence(s)
-
AC159324, CR974568
- UniProtKB/Swiss-Prot
- O88508, Q3TZK8, Q3UH24, Q8CJ60, Q922J0, Q9CSE1
-
NM_007872.5 → NP_031898.1 DNA (cytosine-5)-methyltransferase 3A isoform 1
See identical proteins and their annotated locations for NP_031898.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1, also known as Dnmt3a1). Variants 1 and 3 encode the same isoform (1).
- Source sequence(s)
-
AC159324, CR974568
- Consensus CDS
-
CCDS36397.1
- UniProtKB/Swiss-Prot
- O88508, Q3TZK8, Q3UH24, Q8CJ60, Q922J0, Q9CSE1
- Related
- ENSMUSP00000020991.9, ENSMUST00000020991.15
- Conserved Domains (5) summary
-
- cd05835
Location:286 → 372
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- PTZ00449
Location:1 → 121
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- COG0270
Location:628 → 791
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- TIGR00927
Location:17 → 282
- 2A1904; K+-dependent Na+/Ca+ exchanger
- cd11729
Location:483 → 610
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
NM_153743.5 → NP_714965.1 DNA (cytosine-5)-methyltransferase 3A isoform 2
See identical proteins and their annotated locations for NP_714965.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) represents use of an alternate promoter, compared to variant 1. It differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon. The encoded isoform (2, also known as Dnmt3a2) has a shorter N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC159324
- Consensus CDS
-
CCDS25784.1
- UniProtKB/Swiss-Prot
-
O88508
- Related
- ENSMUSP00000133543.2, ENSMUST00000172689.8
- Conserved Domains (3) summary
-
- cd05835
Location:67 → 153
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:409 → 572
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:264 → 391
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000078.7 Reference GRCm39 C57BL/6J
- Range
-
3851559..3964442
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006514956.4 → XP_006515019.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
See identical proteins and their annotated locations for XP_006515019.1
- UniProtKB/Swiss-Prot
- O88508, Q3TZK8, Q3UH24, Q8CJ60, Q922J0, Q9CSE1
- Conserved Domains (5) summary
-
- cd05835
Location:286 → 372
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- PTZ00449
Location:1 → 121
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- COG0270
Location:628 → 791
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- TIGR00927
Location:17 → 282
- 2A1904; K+-dependent Na+/Ca+ exchanger
- cd11729
Location:483 → 610
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
XM_030246538.1 → XP_030102398.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
- UniProtKB/Swiss-Prot
- O88508, Q3TZK8, Q3UH24, Q8CJ60, Q922J0, Q9CSE1
- Conserved Domains (5) summary
-
- cd05835
Location:286 → 372
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- PTZ00449
Location:1 → 121
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- COG0270
Location:628 → 791
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- TIGR00927
Location:17 → 282
- 2A1904; K+-dependent Na+/Ca+ exchanger
- cd11729
Location:483 → 610
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
XM_030246540.2 → XP_030102400.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
- UniProtKB/Swiss-Prot
- O88508, Q3TZK8, Q3UH24, Q8CJ60, Q922J0, Q9CSE1
- Conserved Domains (5) summary
-
- cd05835
Location:286 → 372
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- PTZ00449
Location:1 → 121
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- COG0270
Location:628 → 791
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- TIGR00927
Location:17 → 282
- 2A1904; K+-dependent Na+/Ca+ exchanger
- cd11729
Location:483 → 610
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
XM_030246539.2 → XP_030102399.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
- UniProtKB/Swiss-Prot
- O88508, Q3TZK8, Q3UH24, Q8CJ60, Q922J0, Q9CSE1
- Conserved Domains (5) summary
-
- cd05835
Location:286 → 372
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- PTZ00449
Location:1 → 121
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- COG0270
Location:628 → 791
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- TIGR00927
Location:17 → 282
- 2A1904; K+-dependent Na+/Ca+ exchanger
- cd11729
Location:483 → 610
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)