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    mcoln2 mucolipin TRP cation channel 2 [ Danio rerio (zebrafish) ]

    Gene ID: 394123, updated on 2-Nov-2024

    Summary

    Official Symbol
    mcoln2provided by ZNC
    Official Full Name
    mucolipin TRP cation channel 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-692
    See related
    Ensembl:ENSDARG00000098918 AllianceGenome:ZFIN:ZDB-GENE-040426-692
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55310
    Summary
    Predicted to enable monoatomic cation channel activity. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in endosome membrane and plasma membrane. Orthologous to human MCOLN2 (mucolipin TRP cation channel 2). [provided by Alliance of Genome Resources, Nov 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See mcoln2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (24623936..24640263)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (24596312..24612639)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101884340 Neighboring gene chloride channel CLIC-like 1 Neighboring gene lysophosphatidic acid receptor 3 Neighboring gene si:rp71-23d18.8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC55310

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables monoatomic cation channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mucolipin-2
    Names
    mucolipin 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201148.1NP_957442.1  mucolipin-2

      See identical proteins and their annotated locations for NP_957442.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044140
      UniProtKB/TrEMBL
      Q803Y8
      Related
      ENSDARP00000139833.2, ENSDART00000160924.2
      Conserved Domains (1) summary
      PLN03223
      Location:370517
      PLN03223; Polycystin cation channel protein; Provisional

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      24623936..24640263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)