atad5b ATPase family AAA domain containing 5b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atad5bprovided by ZNC
Official Full Name: ATPase family AAA domain containing 5bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-338
See related: Ensembl:ENSDARG00000101126 AllianceGenome:ZFIN:ZDB-GENE-030131-338
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rnf135; fb23b03; zgc:66453; wu:fb23b03; dkeyp-97g3.4
Summary: Predicted to enable DNA binding activity and DNA clamp unloader activity. Acts upstream of or within positive regulation of RIG-I signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including eye; female organism; heart; liver; and pleuroperitoneal region. Orthologous to human ATAD5 (ATPase family AAA domain containing 5). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (18544791..18554840)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (22072679..22083829)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb23b03 (e-PCR)
- UniSTS:188973

fb23b03.x1 (e-PCR)
- UniSTS:203074

fc31h10.x1 (e-PCR)
- UniSTS:187978

fe17c10.y1 (e-PCR)
- UniSTS:196258

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables DNA clamp unloader activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of RIG-I signaling pathway	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ATPase family AAA domain-containing protein 5b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082829.2 → NP_001076298.2 ATPase family AAA domain-containing protein 5b

Status: PROVISIONAL

Source sequence(s)

BC057535

UniProtKB/TrEMBL

A0A8M1NDC2, Q6PFI7

Related

ENSDARP00000132410.1, ENSDART00000169599.2

Conserved Domains (1) summary

cl21455
Location:447 → 481

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases