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    abce1 ATP-binding cassette, sub-family E (OABP), member 1 [ Danio rerio (zebrafish) ]

    Gene ID: 406324, updated on 28-Oct-2024

    Summary

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    Official Symbol
    abce1provided by ZNC
    Official Full Name
    ATP-binding cassette, sub-family E (OABP), member 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1995
    See related
    Ensembl:ENSDARG00000007216 AllianceGenome:ZFIN:ZDB-GENE-040426-1995
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56045; wu:fb34c09; wu:fe47b01; wu:fi09g07; zgc:111906
    Summary
    Predicted to enable ATP binding activity; iron ion binding activity; and ribosomal small subunit binding activity. Predicted to be involved in translational initiation and translational termination. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; head; intermediate cell mass of mesoderm; optic tectum; and ventral mesoderm. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease. Orthologous to human ABCE1 (ATP binding cassette subfamily E member 1). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See abce1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (43695594..43718061, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (43894076..43916543, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 10 member 7 Neighboring gene OTU deubiquitinase 4 Neighboring gene anaphase promoting complex subunit 10 Neighboring gene uncharacterized LOC101884517

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis reveals a ribosome constituents disorder involved in the RPL5 downregulated zebrafish model of Diamond-Blackfan anemia. Wan Y, et al. BMC Med Genomics, 2016 Mar 9. PMID 26961822, Free PMC Article
    2. Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Ferrante MI, et al. Hum Mol Genet, 2009 Jan 15. PMID 18971206, Free PMC Article
    3. Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma. Zheng W, et al. PLoS One, 2014. PMID 24633177, Free PMC Article
    4. Evolution of the vertebrate ABC gene family: analysis of gene birth and death. Annilo T, et al. Genomics, 2006 Jul. PMID 16631343
    5. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Dean M, et al. Annu Rev Genomics Hum Genet, 2005. PMID 16124856

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56045

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosomal small subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translational termination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ATP-binding cassette sub-family E member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213051.2 → NP_998216.2  ATP-binding cassette sub-family E member 1

      See identical proteins and their annotated locations for NP_998216.2

      Status: VALIDATED

      Source sequence(s)
      CT630191, CT660911, EH436341, EH443969, EH462331
      UniProtKB/TrEMBL
      A0A8M1PG70, Q6TNW3
      Related
      ENSDARP00000011642.7, ENSDART00000015777.8
      Conserved Domains (5) summary
      cd03236
      Location:78 → 332
      ABC_RNaseL_inhibitor_domain1; The ATP-binding cassette domain 1 of RNase L inhibitor
      cd03237
      Location:348 → 592
      ABC_RNaseL_inhibitor_domain2; The ATP-binding cassette domain 2 of RNase L inhibitor
      COG1245
      Location:4 → 597
      Rli1; Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis]
      pfam00037
      Location:48 → 71
      Fer4; 4Fe-4S binding domain
      pfam04068
      Location:6 → 37
      RLI; Possible Fer4-like domain in RNase L inhibitor, RLI

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      43695594..43718061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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