pnrc2 proline-rich nuclear receptor coactivator 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pnrc2provided by ZNC
Official Full Name: proline-rich nuclear receptor coactivator 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5475
See related: Ensembl:ENSDARG00000053291 AllianceGenome:ZFIN:ZDB-GENE-030131-5475
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb81a06; wu:fb51a04; wu:fb81a06; wu:fd19g06; wu:cegs2777
Summary: Acts upstream of or within nuclear-transcribed mRNA catabolic process. Predicted to be located in cytoplasm. Predicted to be active in P-body and nucleus. Is expressed in nervous system; otic vesicle; and trunk. Orthologous to human PNRC2 (proline rich nuclear receptor coactivator 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 16

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (33101848..33105677, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (33147818..33151647, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pumilio response and AU-rich elements drive rapid decay of Pnrc2-regulated cyclic gene transcripts.
Title: Pumilio response and AU-rich elements drive rapid decay of Pnrc2-regulated cyclic gene transcripts.
Pnrc2 promotes 3'UTR-mediated decay of developmentally-regulated segmentation clock transcripts.
Title: Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation.

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General gene information

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Markers

fb81a06.x1 (e-PCR)
- UniSTS:191597

fb81a06.x1 (e-PCR)
- UniSTS:191598

fj31g10.y1 (e-PCR)
- UniSTS:199051

AI477246 (e-PCR)
- UniSTS:206502

fd19g06.x1 (e-PCR)
- UniSTS:204257

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEA Inferred from Electronic Annotation more info
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in P-body	IBA Inferred from Biological aspect of Ancestor more info
located_in P-body	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: proline-rich nuclear receptor coactivator 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.