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    eamB cysteine/O-acetylserine exporter EamB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947065, updated on 19-Sep-2024

    Summary

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    Official Symbol
    eamB
    Official Full Name
    cysteine/O-acetylserine exporter EamB
    Primary source
    ECOCYC:EG12445
    Locus tag
    b2578
    See related
    ASAP:ABE-0008487
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2576; yfiK
    Summary
    LysE, RhtB family. [More information is available at EcoGene: EG12445]. The yfiK gene product is, as inferred from sequence analysis, an integral membrane protein posessing six predicted transmembrane helices and belonging to the RhtB family of export proteins. [More information is available at EcoCyc: EG12445].
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    Genomic context

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    Sequence:
    NC_000913.3 (2715423..2716010)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase SrmB Neighboring gene putative LysR-type DNA-binding transcriptional regulator YfiE Neighboring gene stress-induced alternate pyruvate formate-lyase subunit Neighboring gene uracil-DNA glycosylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. YfiK from Escherichia coli promotes export of O-acetylserine and cysteine. Franke I, et al. J Bacteriol, 2003 Feb. PMID 12562784, Free PMC Article
    2. Effect of drug transporter genes on cysteine export and overproduction in Escherichia coli. Yamada S, et al. Appl Environ Microbiol, 2006 Jul. PMID 16820466, Free PMC Article
    3. Cell-free complements in vivo expression of the E. coli membrane proteome. Savage DF, et al. Protein Sci, 2007 May. PMID 17456747, Free PMC Article
    4. New ubiquitous translocators: amino acid export by Corynebacterium glutamicum and Escherichia coli. Eggeling L, et al. Arch Microbiol, 2003 Sep. PMID 12879215
    5. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Saier MH Jr, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381841, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables efflux transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cysteine export across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cysteine export across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cysteine/O-acetylserine exporter EamB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2715423..2716010
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417073.1 cysteine/O-acetylserine exporter EamB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417073.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S0FPI0
      Conserved Domains (1) summary
      PRK10323
      Location:1 → 195
      PRK10323; cysteine/O-acetylserine transporter
    Nucleotide Protein
    Heading Accession and Version

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