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    Wdr17 WD repeat domain 17 [ Mus musculus (house mouse) ]

    Gene ID: 244484, updated on 2-Nov-2024

    Summary

    Official Symbol
    Wdr17provided by MGI
    Official Full Name
    WD repeat domain 17provided by MGI
    Primary source
    MGI:MGI:1924662
    See related
    Ensembl:ENSMUSG00000039375 AllianceGenome:MGI:1924662
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3010002I12Rik; B230207L18Rik
    Summary
    Is expressed in brain; cortical plate; eye; olfactory epithelium; and spinal cord. Orthologous to human WDR17 (WD repeat domain 17). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in CNS E18 (RPKM 3.3), cortex adult (RPKM 3.0) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Wdr17 in Genome Data Viewer
    Location:
    8 B1.3; 8 29.28 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (55082316..55180014, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (54629281..54726979, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_21499 Neighboring gene predicted gene, 46039 Neighboring gene spermatogenesis associated 4 Neighboring gene STARR-seq mESC enhancer starr_21500 Neighboring gene STARR-seq mESC enhancer starr_21502 Neighboring gene glycoprotein m6a Neighboring gene predicted gene, 53418 Neighboring gene predicted gene, 57523

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC40755

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    WD repeat-containing protein 17

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001172152.2NP_001165623.1  WD repeat-containing protein 17 isoform 2

      See identical proteins and their annotated locations for NP_001165623.1

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      Consensus CDS
      CCDS52551.1
      UniProtKB/TrEMBL
      Q8C8Y2, Q8CFX0
      Related
      ENSMUSP00000122326.2, ENSMUST00000150488.8
      Conserved Domains (3) summary
      cd00200
      Location:367657
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:333367
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:51441
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. NM_001364215.2NP_001351144.1  WD repeat-containing protein 17 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      cd00200
      Location:293583
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:259293
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:90405
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. NM_001372370.1NP_001359299.1  WD repeat-containing protein 17 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      UniProtKB/TrEMBL
      E9Q271
      Conserved Domains (3) summary
      cd00200
      Location:391681
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:357391
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:75465
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    4. NM_001372371.1NP_001359300.1  WD repeat-containing protein 17 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      UniProtKB/TrEMBL
      E9Q271
      Conserved Domains (3) summary
      cd00200
      Location:391681
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:357391
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:75465
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    5. NM_001372372.1NP_001359301.1  WD repeat-containing protein 17 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      UniProtKB/TrEMBL
      E9Q271
      Conserved Domains (3) summary
      cd00200
      Location:391681
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:357391
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:75465
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    6. NM_001372373.1NP_001359302.1  WD repeat-containing protein 17 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      Consensus CDS
      CCDS90399.1
      UniProtKB/TrEMBL
      H3BLI8, Q8CFX0
      Related
      ENSMUSP00000135805.2, ENSMUST00000175915.8
      Conserved Domains (3) summary
      cd00200
      Location:367657
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:333367
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:51441
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    7. NM_001372374.1NP_001359303.1  WD repeat-containing protein 17 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      COG2319
      Location:1241
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:188478
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:154188
      7WD40; WD40 repeat [structural motif]
    8. NM_001372375.1NP_001359304.1  WD repeat-containing protein 17 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      cd00200
      Location:109399
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:75109
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:2183
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    9. NM_001372376.1NP_001359305.1  WD repeat-containing protein 17 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      Conserved Domains (2) summary
      cd00200
      Location:13303
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:1956
      7WD40; WD40 repeat [structural motif]
    10. NM_001428363.1NP_001415292.1  WD repeat-containing protein 17 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
    11. NM_028220.4NP_082496.3  WD repeat-containing protein 17 isoform 1

      See identical proteins and their annotated locations for NP_082496.3

      Status: VALIDATED

      Source sequence(s)
      AC102933, AC109200
      Consensus CDS
      CCDS22309.2
      UniProtKB/TrEMBL
      G3UVU7, Q8CFX0
      Related
      ENSMUSP00000117710.3, ENSMUST00000144711.9
      Conserved Domains (4) summary
      COG2319
      Location:253665
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:374664
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:340374
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:74281
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      55082316..55180014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154031.1XP_036009924.1  WD repeat-containing protein 17 isoform X12

      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      cd00200
      Location:109399
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:75109
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:2183
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. XM_006509431.4XP_006509494.1  WD repeat-containing protein 17 isoform X5

      See identical proteins and their annotated locations for XP_006509494.1

      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      cd00200
      Location:293583
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:259293
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:90405
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. XM_036154030.1XP_036009923.1  WD repeat-containing protein 17 isoform X11

      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      smart00320
      Location:4988
      WD40; WD40 repeats
      cd00200
      Location:216445
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:208243
      7WD40; WD40 repeat [structural motif]
    4. XM_036154029.1XP_036009922.1  WD repeat-containing protein 17 isoform X9

      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      COG2319
      Location:25295
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:242532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:208242
      7WD40; WD40 repeat [structural motif]
    5. XM_030243543.2XP_030099403.1  WD repeat-containing protein 17 isoform X6

      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      cd00200
      Location:293583
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:259293
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:90405
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    6. XM_006509430.4XP_006509493.1  WD repeat-containing protein 17 isoform X5

      See identical proteins and their annotated locations for XP_006509493.1

      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      cd00200
      Location:293583
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:259293
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:90405
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    7. XM_036154028.1XP_036009921.1  WD repeat-containing protein 17 isoform X8

      Conserved Domains (3) summary
      COG2319
      Location:49319
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:266556
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:232266
      7WD40; WD40 repeat [structural motif]
    8. XM_006509432.3XP_006509495.1  WD repeat-containing protein 17 isoform X7

      UniProtKB/TrEMBL
      E9Q271
      Conserved Domains (3) summary
      COG2319
      Location:49319
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:266556
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:232266
      7WD40; WD40 repeat [structural motif]
    9. XM_006509429.4XP_006509492.1  WD repeat-containing protein 17 isoform X2

      UniProtKB/TrEMBL
      E9Q271
      Conserved Domains (3) summary
      COG2319
      Location:44429
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:376666
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:342376
      7WD40; WD40 repeat [structural motif]
    10. XM_036154025.1XP_036009918.1  WD repeat-containing protein 17 isoform X4

      UniProtKB/TrEMBL
      E9Q271
      Conserved Domains (3) summary
      cd00200
      Location:258594
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:357392
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:74298
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    11. XM_006509426.4XP_006509489.1  WD repeat-containing protein 17 isoform X1

      See identical proteins and their annotated locations for XP_006509489.1

      UniProtKB/TrEMBL
      E9Q271
      Related
      ENSMUSP00000115550.3, ENSMUST00000127511.9
      Conserved Domains (3) summary
      cd00200
      Location:391681
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:357391
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:75465
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    12. XM_006509434.4XP_006509497.1  WD repeat-containing protein 17 isoform X13

      Conserved Domains (2) summary
      cd00200
      Location:13303
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:1956
      7WD40; WD40 repeat [structural motif]
    13. XM_030243544.2XP_030099404.1  WD repeat-containing protein 17 isoform X10

      UniProtKB/TrEMBL
      Q8CFX0
      Conserved Domains (3) summary
      COG2319
      Location:41221
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:168458
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:134168
      7WD40; WD40 repeat [structural motif]
    14. XM_006509427.5XP_006509490.1  WD repeat-containing protein 17 isoform X1

      See identical proteins and their annotated locations for XP_006509490.1

      UniProtKB/TrEMBL
      E9Q271
      Conserved Domains (3) summary
      cd00200
      Location:391681
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:357391
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:75465
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    15. XM_030243540.2XP_030099400.1  WD repeat-containing protein 17 isoform X3

      UniProtKB/TrEMBL
      Q8C8Y2, Q8CFX0
      Conserved Domains (3) summary
      cd00200
      Location:367657
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:333367
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:51441
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RNA

    1. XR_001778439.3 RNA Sequence

    2. XR_004934823.1 RNA Sequence