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    Lrrc37 leucine rich repeat containing 37 [ Mus musculus (house mouse) ]

    Gene ID: 380730, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Lrrc37provided by MGI
    Official Full Name
    leucine rich repeat containing 37provided by MGI
    Primary source
    MGI:MGI:2685730
    See related
    Ensembl:ENSMUSG00000034239 AllianceGenome:MGI:2685730
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm884
    Summary
    Orthologous to several human genes including LRRC37A2 (leucine rich repeat containing 37 member A2); LRRC37A3 (leucine rich repeat containing 37 member A3); and LRRC37A (leucine rich repeat containing 37A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 7.9) See more
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    Genomic context

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    See Lrrc37 in Genome Data Viewer
    Location:
    11 E1; 11 67.38 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (103425403..103512309, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (103534577..103621483, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9376 Neighboring gene STARR-positive B cell enhancer ABC_E3027 Neighboring gene predicted gene, 39397 Neighboring gene STARR-seq mESC enhancer starr_30849 Neighboring gene STARR-seq mESC enhancer starr_30850 Neighboring gene leucine rich repeat containing 37A Neighboring gene STARR-seq mESC enhancer starr_30851 Neighboring gene STARR-seq mESC enhancer starr_30852 Neighboring gene STARR-seq mESC enhancer starr_30853 Neighboring gene STARR-seq mESC enhancer starr_30854 Neighboring gene STARR-seq mESC enhancer starr_30855 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene RIKEN cDNA 1700072I22 gene Neighboring gene lysozyme-like 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Evolutionary dynamism of the primate LRRC37 gene family. Giannuzzi G, et al. Genome Res, 2013 Jan. PMID 23064749, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 37A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033434.2 → NP_001028606.2  leucine-rich repeat-containing protein 37A

      Status: VALIDATED

      Source sequence(s)
      AK029868, AL732606
      Consensus CDS
      CCDS48952.1
      UniProtKB/TrEMBL
      E9Q472, Q3V3Y5
      Related
      ENSMUSP00000129662.2, ENSMUST00000167262.2
      Conserved Domains (5) summary
      sd00031
      Location:600 → 623
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:578 → 599
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:601 → 658
      LRR_8; Leucine rich repeat
      pfam14914
      Location:1248 → 1394
      LRRC37AB_C; LRRC37A/B like protein 1 C-terminal domain
      pfam15779
      Location:67 → 131
      LRRC37; Leucine-rich repeat-containing protein 37 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      103425403..103512309 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246104.1 → XP_030101964.1  leucine-rich repeat-containing protein 37A isoform X1

      UniProtKB/TrEMBL
      A2A9H6
      Related
      ENSMUSP00000058511.7, ENSMUST00000059279.13
      Conserved Domains (5) summary
      sd00031
      Location:2858 → 2881
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:2836 → 2857
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:2859 → 2916
      LRR_8; Leucine rich repeat
      pfam14914
      Location:3506 → 3652
      LRRC37AB_C; LRRC37A/B like protein 1 C-terminal domain
      pfam15779
      Location:1115 → 1187
      LRRC37; Leucine-rich repeat-containing protein 37 family
    Nucleotide Protein Strain
    Heading Accession and Version

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