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    dnd1 DND microRNA-mediated repression inhibitor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 373074, updated on 28-Oct-2024

    Summary

    Official Symbol
    dnd1provided by ZNC
    Official Full Name
    DND microRNA-mediated repression inhibitor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030828-4
    See related
    Ensembl:ENSDARG00000022813 AllianceGenome:ZFIN:ZDB-GENE-030828-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dnd; cb736; wu:fi22d10; zgc:111864
    Summary
    Enables mRNA 3'-UTR binding activity. Acts upstream of or within several processes, including germ cell migration; heart contraction; and mRNA stabilization. Located in P granule and germ cell nucleus. Is expressed in blastodisc; brain; heart; reproductive system; and unfertilized egg. Orthologous to human DND1 (DND microRNA-mediated repression inhibitor 1). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    NEW
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    Genomic context

    See dnd1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (7397889..7409019, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (7091480..7102610, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 11 Neighboring gene histidyl-tRNA synthetase Neighboring gene GDNF family receptor alpha 3 Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene bromodomain containing 8b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA 3'-UTR binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in P granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    dead end protein 1
    Names
    drDnd1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212795.1NP_997960.1  dead end protein 1

      See identical proteins and their annotated locations for NP_997960.1

      Status: PROVISIONAL

      Source sequence(s)
      AY225448
      UniProtKB/Swiss-Prot
      Q4VBK4, Q7T1H5
      UniProtKB/TrEMBL
      B2GPX0
      Related
      ENSDARP00000035017.7, ENSDART00000036463.9
      Conserved Domains (3) summary
      cd12493
      Location:138220
      RRM2_DND1; RNA recognition motif 2 found in vertebrate dead end protein homolog 1 (DND1)
      pfam14709
      Location:323403
      DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
      cl17169
      Location:59136
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      7397889..7409019 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)