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    hexim1 HEXIM P-TEFb complex subunit 1 [ Danio rerio (zebrafish) ]

    Gene ID: 562319, updated on 18-Sep-2024

    Summary

    Official Symbol
    hexim1provided by ZNC
    Official Full Name
    HEXIM P-TEFb complex subunit 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4637
    See related
    Ensembl:ENSDARG00000036482 AllianceGenome:ZFIN:ZDB-GENE-030131-4637
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hexim; fd44h02; wu:fd44h02; zgc:162976
    Summary
    Predicted to enable 7SK snRNA binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Acts upstream of or within protein-containing complex assembly. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in head. Orthologous to several human genes including HEXIM1 (HEXIM P-TEFb complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See hexim1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (15565344..15566922, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (15523037..15524615, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene plexin domain containing 1 Neighboring gene Rho GTPase activating protein 23b Neighboring gene acyl-CoA binding domain containing 4 Neighboring gene phospholipase C, delta 3b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC162976

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 7SK snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cyclin-dependent protein serine/threonine kinase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cyclin-dependent protein serine/threonine kinase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables snRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein HEXIM1
    Names
    hexamethylene bis-acetamide inducible 1
    protein HEXIM

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098389.1NP_001091859.1  protein HEXIM1

      See identical proteins and their annotated locations for NP_001091859.1

      Status: PROVISIONAL

      Source sequence(s)
      BC141797
      UniProtKB/Swiss-Prot
      A5D8S8
      Related
      ENSDARP00000053002.4, ENSDART00000053003.5
      Conserved Domains (1) summary
      pfam15313
      Location:114255
      HEXIM; Hexamethylene bis-acetamide-inducible protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      15565344..15566922 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)