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    mis12 MIS12 kinetochore complex component [ Danio rerio (zebrafish) ]

    Gene ID: 393349, updated on 17-Aug-2024

    Summary

    Official Symbol
    mis12provided by ZNC
    Official Full Name
    MIS12 kinetochore complex componentprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1372
    See related
    Ensembl:ENSDARG00000026454 AllianceGenome:ZFIN:ZDB-GENE-040426-1372
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:64116
    Summary
    Predicted to be involved in kinetochore assembly; mitotic sister chromatid segregation; and protein localization to kinetochore. Predicted to act upstream of or within cell division and mitotic cell cycle. Predicted to be located in kinetochore and nucleus. Predicted to be part of nuclear MIS12/MIND complex. Orthologous to human MIS12 (MIS12 kinetochore complex component). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 5
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (58992412..58996199, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (58322703..58326490, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene TLC domain containing 5b Neighboring gene melanoma cell adhesion molecule a Neighboring gene uncharacterized LOC110438666 Neighboring gene derlin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC64116

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in kinetochore assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic sister chromatid segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of MIS12/MIND type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200378.1NP_956672.1  protein MIS12 homolog

      See identical proteins and their annotated locations for NP_956672.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053260
      UniProtKB/TrEMBL
      Q7T344
      Related
      ENSDARP00000032207.3, ENSDART00000033923.6
      Conserved Domains (2) summary
      pfam05859
      Location:16149
      Mis12; Mis12 protein
      pfam11898
      Location:127175
      DUF3418; Domain of unknown function (DUF3418)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      58992412..58996199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)