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    hoxd10a homeobox D10a [ Danio rerio (zebrafish) ]

    Gene ID: 30404, updated on 2-Nov-2024

    Summary

    Official Symbol
    hoxd10aprovided by ZNC
    Official Full Name
    homeobox D10aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990415-116
    See related
    Ensembl:ENSDARG00000057859 AllianceGenome:ZFIN:ZDB-GENE-990415-116
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    z-82; hoxd10; HOX-D10; hoxd-10
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in mesenchyme; mesenchyme pectoral fin; oocyte; pectoral fin bud; and pectoral fin field. Human ortholog(s) of this gene implicated in congenital vertical talus. Orthologous to human HOXD10 (homeobox D10). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See hoxd10a in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (1967706..1970047, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (1966909..1969250, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene homeobox D3a Neighboring gene microRNA 10b-1 Neighboring gene homeobox D9a Neighboring gene homeobox D11a Neighboring gene homeobox D12a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    homeobox protein Hox-D10a
    Names
    homeo box D10a
    homeobox gene D-10
    homeobox protein Hox-C10
    hox-C10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131166.2NP_571241.2  homeobox protein Hox-D10a

      See identical proteins and their annotated locations for NP_571241.2

      Status: PROVISIONAL

      Source sequence(s)
      BC071329, CK864624, CT704711
      UniProtKB/Swiss-Prot
      A8E5N6, O57371, P79730, P79731, Q6IQS5, Q90469
      Related
      ENSDARP00000075055.3, ENSDART00000080608.4
      Conserved Domains (2) summary
      COG5576
      Location:204321
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:261314
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      1967706..1970047 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)