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    noc2l NOC2-like nucleolar associated transcriptional repressor [ Danio rerio (zebrafish) ]

    Gene ID: 58013, updated on 28-Oct-2024

    Summary

    Official Symbol
    noc2lprovided by ZNC
    Official Full Name
    NOC2-like nucleolar associated transcriptional repressorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000607-75
    See related
    Ensembl:ENSDARG00000001754 AllianceGenome:ZFIN:ZDB-GENE-000607-75
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    id:ibd5110; zgc:195326
    Summary
    Predicted to enable histone binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and ribosomal large subunit biogenesis. Predicted to be located in nucleus. Predicted to be part of Noc1p-Noc2p complex and Noc2p-Noc3p complex. Predicted to be active in nucleolus and nucleoplasm. Is expressed in immature eye. Orthologous to human NOC2L (NOC2 like nucleolar associated transcriptional repressor). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
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    Genomic context

    See noc2l in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (23126130..23179417, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (23199579..23252866, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101883493 Neighboring gene sterile alpha motif domain containing 11 Neighboring gene kelch-like family member 17 Neighboring gene pleckstrin homology domain containing, family N member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Noc1p-Noc2p complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Noc2p-Noc3p complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nucleolar complex protein 2 homolog
    Names
    nucleolar complex associated 2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003830.2NP_001003830.2  nucleolar complex protein 2 homolog

      Status: VALIDATED

      Source sequence(s)
      AL845437, CK029021, EB924499
      UniProtKB/TrEMBL
      A0A8M1N1T6, F1QFC4
      Related
      ENSDARP00000086095.6, ENSDART00000091662.6
      Conserved Domains (1) summary
      pfam03715
      Location:325620
      Noc2; Noc2p family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      23126130..23179417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353600.3XP_017209089.1  nucleolar complex protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8M6YXS2

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395148.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      48554..101841 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)