U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    xirp2a xin actin binding repeat containing 2a [ Danio rerio (zebrafish) ]

    Gene ID: 559746, updated on 17-Aug-2024

    Summary

    Official Symbol
    xirp2aprovided by ZNC
    Official Full Name
    xin actin binding repeat containing 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040108-7
    See related
    Ensembl:ENSDARG00000071113 AllianceGenome:ZFIN:ZDB-GENE-040108-7
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    xirp2; sb:cb1045; wu:fc12g12
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to act upstream of or within actin filament bundle assembly; heart development; and negative regulation of actin filament depolymerization. Predicted to be located in cell junction. Predicted to colocalize with focal adhesion and stress fiber. Is expressed in several structures, including fin; forebrain; musculature system; pericardial region; and somite. Orthologous to human XIRP2 (xin actin binding repeat containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See xirp2a in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (10172574..10234683, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (9937035..10007504, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene ATPase copper transporting beta Neighboring gene UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1a Neighboring gene sodium channel, voltage-gated, type I like, alpha b Neighboring gene cordon-bleu WH2 repeat protein-like 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    colocalizes_with stress fiber IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    xin actin-binding repeat-containing protein 2
    Names
    Xin beta6
    epithelial protein lost in neoplasm
    xin actin-binding repeat containing 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      10172574..10234683 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477013.1XP_021332688.1  xin actin-binding repeat-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q058, F8W4U4
      Related
      ENSDARP00000124135.1, ENSDART00000148876.2
      Conserved Domains (1) summary
      pfam08043
      Location:952965
      Xin; Xin repeat
    2. XM_005165785.4XP_005165842.1  xin actin-binding repeat-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BD29
      Conserved Domains (1) summary
      pfam08043
      Location:951964
      Xin; Xin repeat
    3. XM_009302196.3XP_009300471.1  xin actin-binding repeat-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AT61
      Conserved Domains (1) summary
      pfam08043
      Location:820833
      Xin; Xin repeat