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    hpxb hemopexin b [ Danio rerio (zebrafish) ]

    Gene ID: 767787, updated on 12-Sep-2024

    Summary

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    Official Symbol
    hpxbprovided by ZNC
    Official Full Name
    hemopexin bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-800
    See related
    AllianceGenome:ZFIN:ZDB-GENE-060929-800
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hbxb; smarca2; zgc:152945
    Summary
    Predicted to be involved in heme metabolic process. Predicted to be active in extracellular space. Orthologous to human HPX (hemopexin). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See hpxb in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (2396041..2414063, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (2885496..2903397, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 Neighboring gene dual specificity phosphatase 29-like Neighboring gene uncharacterized LOC100333749 Neighboring gene uncharacterized LOC110437962

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phagocytosis of mycobacteria by zebrafish macrophages is dependent on the scavenger receptor Marco, a key control factor of pro-inflammatory signalling. Benard EL, et al. Dev Comp Immunol, 2014 Dec. PMID 25086293
    2. Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Chernyavskaya Y, et al. Development, 2017 Aug 15. PMID 28698226, Free PMC Article
    3. Transcriptomic analyses of sexual dimorphism of the zebrafish liver and the effect of sex hormones. Zheng W, et al. PLoS One, 2013. PMID 23349717, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC152945

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    hemopexin; uncharacterized protein LOC767787

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      2396041..2414063 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173448.5 → XP_005173505.1  hemopexin

      UniProtKB/TrEMBL
      A0A8M2BKS1
      Conserved Domains (2) summary
      cd00094
      Location:38 → 232
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cl02471
      Location:246 → 433
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001076754.1: Suppressed sequence

      Description
      NM_001076754.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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