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    YPS6 aspartyl protease [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854857, updated on 2-Nov-2024

    Summary

    Official Symbol
    YPS6
    Official Full Name
    aspartyl protease
    Primary source
    SGD:S000001478
    Locus tag
    YIR039C
    See related
    AllianceGenome:SGD:S000001478; FungiDB:YIR039C; VEuPathDB:YIR039C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable aspartic-type endopeptidase activity. Involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See YPS6 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (430498..432111, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene peroxiredoxin HYR1 Neighboring gene bifunctional glutathione transferase/peroxidase Neighboring gene seripauperin PAU15 Neighboring gene uncharacterized protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables aspartic-type endopeptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fungal-type cell wall organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell periphery IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    aspartyl protease
    NP_012305.3
    • Putative GPI-anchored aspartic protease; member of the yapsin family of proteases involved in cell wall growth and maintenance

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      430498..432111 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179561.3NP_012305.3  TPA: aspartyl protease [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012305.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVX0, E9PAD7, P40583
      UniProtKB/TrEMBL
      G2WFW7
      Conserved Domains (1) summary
      cd05474
      Location:65428
      SAP_like; SAPs, pepsin-like proteinases secreted from pathogens to degrade host proteins